Evidence map›Paper›PMID 38533939›Full record

SynthesisJournal of the American Heart Association2024

Impact of Prosthesis-Patient Mismatch After Surgical Aortic Valve Replacement: Systematic Review and Meta-Analysis of Reconstructed Time-to-Event Data of 122 989 Patients With 592 952 Patient-Years.

Michel Pompeu Sá, Xander Jacquemyn, Jef Van den Eynde, Danny Chu, Derek Serna-Gallegos, Tjark Ebels, Marie-Annick Clavel, Philippe Pibarot, Ibrahim Sultan

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Review
  2. Prosthesis-Patient Mismatch in All-Comer Patients Undergoing Newer-Generation Self-Expanding Transcatheter Aortic Valve Replacement.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Introducing the Concept of Label-Prosthesis Mismatch and Its Classification.Structural heart : the journal of the Heart Team · 2026
    Article
  8. Review
  9. Long-Term Impact of Prosthesis-Patient Mismatch After Transcatheter Aortic Valve Replacement in Patients With Small Aortic Annuli.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michel Pompeu SáDepartment of Cardiothoracic Surgery University of Pittsburgh PA USA.ORCID 0000-0001-5356-2996
Xander JacquemynDepartment of Cardiovascular Sciences KU Leuven Leuven Belgium.ORCID 0000-0001-8421-0686
Jef Van den EyndeDepartment of Cardiovascular Sciences KU Leuven Leuven Belgium.ORCID 0000-0002-5606-376X
Danny ChuDepartment of Cardiothoracic Surgery University of Pittsburgh PA USA.ORCID 0000-0002-2183-6072
Derek Serna-GallegosDepartment of Cardiothoracic Surgery University of Pittsburgh PA USA.ORCID 0000-0002-5991-6385
Tjark EbelsDepartment of Cardiothoracic Surgery, University Medical Center Groningen University of Groningen The Netherlands.ORCID 0000-0002-7124-0058
Marie-Annick ClavelCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec Québec City Québec Canada.ORCID 0000-0002-8924-740X
Philippe PibarotCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec Québec City Québec Canada.ORCID 0000-0002-3607-279X
Ibrahim SultanDepartment of Cardiothoracic Surgery University of Pittsburgh PA USA.ORCID 0000-0002-1737-4012

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt remains controversial whether prosthesis-patient mismatch (PPM) impacts long-term outcomes after surgical aortic valve replacement. We aimed to evaluate the association of PPM with mortality, rehospitalizations, and aortic valve reinterventions. METHODS AND

resultsWe performed a systematic review with meta-analysis of reconstructed time-to-event data of studies published by March 2023 (according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses). Sixty-five studies met our eligibility criteria and included 122 989 patients (any PPM: 68 332 patients, 55.6%). At 25 years of follow-up, the survival rates were 11.8% and 20.6% in patients with and without any PPM, respectively (hazard ratio [HR], 1.16 [95% CI, 1.13-1.18],

conclusionsThe results of the present study suggest that any degree of PPM is associated with poorer long-term outcomes following surgical aortic valve replacement and provide support for implementation of preventive strategies to avoid PPM after surgical aortic valve replacement.

Indexed as

Aortic ValveHeart Valve ProsthesisHeart Valve Prosthesis ImplantationAortic Valve StenosisFemaleHumansMalePatient ReadmissionPostoperative ComplicationsProsthesis DesignReoperationRisk AssessmentRisk FactorsTime FactorsTreatment Outcomeaortic valve replacementcardiac surgical procedurescardiovascular surgical proceduresheart valve diseasesheart valve prosthesis implantationmeta‐analysis

Identifiers

PMID38533939
PMCPMC11179750

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.