Evidence map›Paper›PMID 38533934›Full record

ArticleJournal of neurophysiology2024

PICking out progressive PIC alterations in amyotrophic lateral sclerosis.

Andrew J Deutsch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Andrew J DeutschDepartment of Biomedical, Industrial, and Human Factors Engineering, College of Engineering and Computer ScienceWright State UniversityDaytonOhioUnited States.ORCID 0009-0001-3992-7642

Funding

The impact of neuromodulatory state on the excitability changes of motoneurons and the motor pool in ALSR01NS091836 · NINDS · WRIGHT STATE UNIVERSITY · PI Sherif M Elbasiouny · 2015 to 2026
$4.7M
Neuronal mechanisms involved in aging and ADR01AG067758 · NIA · OHIO UNIVERSITY ATHENS · PI ARNOLD, WILLIAM DAVID, CLARK, BRIAN C · 2021 to 2025
$4.1M
Excitability Dysfunction Mechanisms Underlying the TDP43-Dependent ALS and FTD PathogenesisR01NS131816 · NINDS · WRIGHT STATE UNIVERSITY · PI Sherif M Elbasiouny · 2023 to 2026
$2.9M
HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS091836HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS131816HHS | NIH | National Institute on Aging (NIA) AG067758NIA NIH HHS R01 AG067758NINDS NIH HHS R01 NS091836NINDS NIH HHS R01 NS131816
6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that causes motoneuron death. Alterations to motoneuron excitability in ALS are suspected to contribute to motoneuron degeneration. Therefore, mechanisms underlying changes in motoneuron excitability are being thoroughly investigated. A recent publication from Trajano et al. (Trajano GS, Orssatto LB, McCombe PA, Rivlin W, Tang L, Henderson RD.

Indexed as

Amyotrophic Lateral SclerosisMotor NeuronsHumansALSexcitotoxicitymotor unitpersistent inward currents

Identifiers

PMID38533934
PMCPMC11383380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.