Evidence map›Paper›PMID 38533295›Full record

ArticleCritical care explorations2024

Hemodynamic Determinants of Cardiac Surgery-Associated Acute Kidney Injury.

Sevag Demirjian, Faisal Bakaeen, W H Wilson Tang, Chase Donaldson, Jon Taliercio, Anne Huml, Crystal A Gadegbeku, A Marc Gillinov, Steven Insler

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sevag DemirjianDepartment of Kidney Medicine, Cleveland Clinic, Cleveland, OH.
Faisal BakaeenDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH.
W H Wilson TangDepartment of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH.
Chase DonaldsonDepartment of Intensive Care and Resuscitation, Cleveland Clinic, Cleveland, OH.
Jon TaliercioDepartment of Kidney Medicine, Cleveland Clinic, Cleveland, OH.
Anne HumlDepartment of Kidney Medicine, Cleveland Clinic, Cleveland, OH.
Crystal A GadegbekuDepartment of Kidney Medicine, Cleveland Clinic, Cleveland, OH.
A Marc GillinovDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH.
Steven InslerDepartment of Intensive Care and Resuscitation, Cleveland Clinic, Cleveland, OH.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesExamine the: 1) relative role of hemodynamic determinants of acute kidney injury (AKI) obtained in the immediate postcardiac surgery setting compared with established risk factors, 2) their predictive value, and 3) extent mediation via central venous pressure (CVP) and mean arterial pressure (MAP).

designRetrospective observational study. The main outcome of the study was moderate to severe AKI, per kidney disease: improving global outcomes, within 14 days of surgery.

settingU.S. academic medical center. PATIENTS: Adult patients undergoing cardiac surgery between January 2000 and December 2019 (

interventionsNone. MEASUREMENTS AND

resultsThe median age of the cohort was 67 years (58, 75), and 33% were female; 70% had chronic hypertension, 29% had congestive heart failure, and 3% had chronic kidney disease. In a multivariable model, which included comorbidities and traditional intraoperative risk factors, CVP (

conclusionsHemodynamic factors measured within a few hours of surgery showed a strong association with AKI. Furthermore, determinants of kidney perfusion, namely CVP and arterial pressure are interdependent; as are constituents of stroke volume, that is, cardiac output and heart rate.

Indexed as

acute kidney injurycardiac indexcardiac surgerycentral venous pressureheart ratemean arterial pressure

Identifiers

PMID38533295
PMCPMC10962899
OpenAlexW4393079731

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.