Evidence map›Paper›PMID 38533269›Full record

Trial reportOpen forum infectious diseases2024

Analysis of National Institutes of Health Funding for the COVID-19 Pandemic.

Adishesh K Narahari, Taylor M Horgan, Anirudha S Chandrabhatla, D Chris Gist, Paranjay D Patel, Mark A Lantieri, Jeffrey M Sturek, Claire L Davis, Patrick E H Jackson, Taison D Bell

Abstract readClinical Trial
In one paragraph

Trial report in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adishesh K NarahariDivision of Cardiothoracic Surgery, University of Virginia School of Medicine, Charlottesville, Virginia, USA.ORCID https://orcid.org/0000-0002-8708-9161
Taylor M HorganSchool of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Anirudha S ChandrabhatlaSchool of Medicine, University of Virginia, Charlottesville, Virginia, USA.
D Chris GistSchool of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Paranjay D PatelDepartment of Cardiovascular Surgery, Houston Methodist Hospital, Houston, Texas, USA.
Mark A LantieriDepartment of Orthopedic Surgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Jeffrey M SturekSchool of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Claire L DavisSchool of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Patrick E H JacksonSchool of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Taison D BellSchool of Medicine, University of Virginia, Charlottesville, Virginia, USA.

Funding

Role of Pannexin-1 in Chemotherapy-Induced Neuropathic PainF30CA236370 · NCI · UNIVERSITY OF VIRGINIA · PI NARAHARI, ADISHESH · 2019 to 2021
$118k
NCI NIH HHS F30 CA236370
6 · The paper itself

Abstract

Background: Evaluating the National Institute's Health's (NIH's) response to the coronavirus disease 2019 (COVID-19) pandemic via grants and clinical trials is crucial to determining the impact they had on aiding US citizens. We determined how the NIH's funding for COVID-19 research was disbursed and used by various institutions across the United States. Methods: We queried NIH RePORTER and isolated COVID-19-related grants from January 2020 to December 2021. We analyzed grant type, geographical location, and awardee institution. Manuscripts published from these grants were quantitatively analyzed. COVID-19 clinical trials were mapped and distances from counties to clinical trial sites were calculated using ArcGis. Results: A total of 2401 COVID-19 NIH grants resulted in 14 654 manuscripts from $4.2 billion and generated more than 150 000 citations. R01s make up 32% of grants (763/2401) and 8% of funding ($329 million). UM1 grants account for the majority of funding (30.8%; $1.3 Billion). Five states received 50.6% of funding: North Carolina, Washington, New York, California, and Massachusetts. Finally, of the 1806 clinical trials across 1266 sites in the United States, the majority were in metropolitan areas in close proximity to areas of high COVID-19 disease burden. Conclusions and Relevance: Evaluating the outcome of the NIH's response to the COVID-19 pandemic is of interest to the general public. The present study finds that the NIH disbursed more than $4 billion in funding to large consortiums and clinical trials to develop diagnostics, therapeutics, and vaccines. Approximately 8% of funding was used for R01 grants. Clinical trial sites were generally located in areas of high COVID-19 burden.

Indexed as

clinical trialsCOVID-19grantsNIH fundingSARS CoV-2

Identifiers

PMID38533269
PMCPMC10965119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.