Evidence map›Paper›PMID 38533147›Full record

ArticleCureus2024

Osteopathic Approach in the Stimulation of the Endocannabinoid System: A Case Report.

Caterina Buonomini, Oliviero Bonetti, Emanuele Novelli

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Caterina BuonominiOsteopathic, Biological, Medical Research, Omicron Beta Research, Roma, ITA.
Oliviero BonettiOsteopathic, Biological, Medical Research, Omicron Beta Research, Roma, ITA.
Emanuele NovelliFacoltà di Medicina e Chirurgia, Università di Roma Tor Vergata, Roma, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endocannabinoid system is an important neuromodulatory system responsible for maintaining homeostasis in the biological system. Similarly, the autonomic nervous system is important to control involuntary bodily functions such as thermoregulation, regulation of heart rate and sleep latency. The endocannabinoid system and the autonomic nervous system can be modified by osteopathic manipulative techniques. In this report, we present a case of a 53-year-old patient with comorbidities, habitual cannabis use, and disorders associated with the endocannabinoid system and autonomic nervous system, on whom the cranial technique of the fourth ventricle (CV4) was performed. The results obtained from the Pittsburgh Questionnaire and the Health Survey 36 (SF-36) Questionnaire were encouraging. The patient decreased tetrahydrocannabinol (THC) consumption. Her sleep quality and health improved, thus improving her quality of life. CV4 aimed to influence the functioning of the patient's autonomic nervous system and consequently the endocannabinoid system. Further research using randomized controlled trials will be important to have measurable and objective data on this topic.

Indexed as

autonomic nervous system modulationcompression of fourth ventriclecranial ostheopathyendocannabinoid systemosteopathic manipulative medicine

Identifiers

PMID38533147
PMCPMC10964046

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.