Evidence map›Paper›PMID 38532931›Full record

ArticleFrontiers in oncology2024

Hemophagocytic lymphohistiocytosis during treatment of intracranial multifocal germinoma: a case report and literature review.

Ting Guo, Zichun Liu, Yixin Chen, Yangyang Cheng, Kaitong He, Xin Lin, Mingzhu Wang, Yihua Sun

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ting GuoDepartment of Clinical Laboratory, Fengcheng Hospital of Fengxian District, Shanghai, China.
Zichun LiuDepartment of Clinical Laboratory, Fengcheng Hospital of Fengxian District, Shanghai, China.
Yixin ChenDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin, China.
Yangyang ChengDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin, China.
Kaitong HeDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin, China.
Xin LinDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin, China.
Mingzhu WangDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin, China.
Yihua SunDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin, China.
Harbin Medical University · CNThird Affiliated Hospital of Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemophagocytic lymphohistiocytosis (HLH), also known as hemophagocytic syndrome (HPS), is a benign histiocytosis with hyperreactive proliferation of the mononuclear phagocyte system caused by immune function abnormalities, which often occurs under the background of genetic mutations, inflammation, infection or tumors. Because the research on malignancy-associated HLH (M-HLH) is focused on hematological malignancies, reports on HLH secondary to solid tumors are rare. In this case, we report a 14-year-old girl who developed HLH during treatment for intracranial multifocal germinoma, and the disease was controlled after hormone combined with etoposide(VP-16) and other related treatments. To our knowledge, there have been no documented cases of HLH caused by intracranial multifocal germinoma.

Indexed as

case reporthemophagocytic lymphohistiocytosishemophagocytic syndromeintracranial multifocal germinomamalignancy

Identifiers

PMID38532931
PMCPMC10963405
OpenAlexW4392712560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.