Evidence map›Paper›PMID 38532798›Full record

ReviewNon-coding RNA research2024

Epigenetic modulation of long noncoding RNA H19 in oral squamous cell carcinoma-A narrative review.

Peramaiyan Rajendran, Ramya Sekar, Basem M Abdallah, Shazia Fathima Jh, Enas M Ali, Selvaraj Jayaraman, Salaheldin Abdelraouf Abdelsalam, Vishnupriya Veeraraghavan

Open access · goldAbstract readReview
In one paragraph

Review in Non-coding RNA research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Peramaiyan RajendranDepartment of Biological Sciences, College of Science, King Faisal University, Al-Ahsa, 31982, Saudi Arabia.
Ramya SekarDepartment of Oral Pathology & Microbiology, Meenakshi Ammal Dental College & Hospital, Alapakkam Main Road, Maduravoyal, Chennai, 95, TN, India.
Basem M AbdallahDepartment of Biological Sciences, College of Science, King Faisal University, Al-Ahsa, 31982, Saudi Arabia.
Shazia Fathima JhCOMManD, Department of Biochemistry, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Velappanchavadi, Chennai, 600 077, Tamil Nadu, India.
Enas M AliDepartment of Biological Sciences, College of Science, King Faisal University, Al-Ahsa, 31982, Saudi Arabia.
Selvaraj JayaramanCOMManD, Department of Biochemistry, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Velappanchavadi, Chennai, 600 077, Tamil Nadu, India.
Salaheldin Abdelraouf AbdelsalamDepartment of Biological Sciences, College of Science, King Faisal University, Al-Ahsa, 31982, Saudi Arabia.
Vishnupriya VeeraraghavanCOMManD, Department of Biochemistry, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Velappanchavadi, Chennai, 600 077, Tamil Nadu, India.
King Faisal University · SASaveetha University · INCairo University · EGMeenakshi Academy of Higher Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) showed a seemingly increasing incidence in the last decade. In India, despite the use of tobacco decreased rapidly, in the past five years, the incidence pattern of OSCC over gender and age showed a drastic shift. About 51 % of the head and neck cancers are not associated with habits. Studies exploring various contributing factors in the incidence of this malignancy have documented. Recently, the epigenetic factors associated with the induction and progression of OSCC were explored. More than 90 % of the human genome is made up of non-coding transcriptome, which believed to be noises. However, these non-coding RNAs were identified to be the major epigenetic modulators, which raises concern over incidence of carcinoma in non-habit patients. H19 is a long non coding RNA which proved to be an effective biomarker in various carcinoma. Its role in oral squamous cell cancer was not investigated in depth. This review discusses in detail the various epigenetic role of H19 in inducing oral carcinogenesis.

Indexed as

BiomarkerH19lncRNAmicroRNAOral cancer

Identifiers

PMID38532798
PMCPMC10963247
OpenAlexW4391429427

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.