Evidence map›Paper›PMID 38532722›Full record

ArticleRenal failure2023

Increased extracellular water/body mass is associated with functional impairment in hemodialysis patients.

Lin Zhan, Lu Liu, Jing Yuan, Chaomin Zhou, Yan Zha

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Renal failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lin ZhanCentral laboratory of Guizhou Provincial People's Hospital, Guiyang, China.
Lu LiuNHC Key Laboratory of Pulmonary Immune-related Diseases, Renal Division, Department of Medicine, Guizhou Provincial People's Hospital, Guiyang, China.
Jing YuanNHC Key Laboratory of Pulmonary Immune-related Diseases, Renal Division, Department of Medicine, Guizhou Provincial People's Hospital, Guiyang, China.
Chaomin ZhouNHC Key Laboratory of Pulmonary Immune-related Diseases, Renal Division, Department of Medicine, Guizhou Provincial People's Hospital, Guiyang, China.
Yan ZhaNHC Key Laboratory of Pulmonary Immune-related Diseases, Renal Division, Department of Medicine, Guizhou Provincial People's Hospital, Guiyang, China.ORCID 0000-0002-1185-455X
Guizhou Provincial People's Hospital · CNGuiyang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional impairment, malnutrition and fluid overload are prevalent in patients undergoing maintenance hemodialysis (MHD). The extracellular water/body cell mass ratio (ECW/BCM) is a new indicator reflecting fluid overload and malnutrition. A previous study has suggested that it performs better than other indices in assessing fluid status. This study investigates the relationship between pre-dialysis whole-body ECW/BCM and physical function in MHD patients.

methodsWe conducted a multicenter, cross-sectional study in Guizhou Province in Southwest China. The Karnofsky Performance Status (KPS) was used to evaluate patients' functional status. Patients with KPS scores of ≤ 80 were considered to have a functional impairment. The body composition was measured using the body composition monitor (BCM), and the value of the ECW/BCM ratio was calculated. The subjects were classified into three groups according to ECW/BCM tertiles. Multiple logistic regression models and interactive analyses were conducted.

resultsThe final analysis included 2818 subjects. Multivariate logistic regression analyses showed that compared with the lowest tertile (tertile 1), the adjusted odds ratio of functional impairment were 1.95 (95% CI: 1.21-3.13,

conclusionsElevated ECW/BCM is independently linked to an increased risk of functional impairment in patients with MHD.

Indexed as

Diabetes MellitusHeart FailureMalnutritionStrokeWater-Electrolyte ImbalanceBody CompositionBody WaterCross-Sectional StudiesElectric ImpedanceHumansRenal DialysisExtracellular water and body cell mass ratiofluid overloadhemodialysisthe Karnofsky performance status score

Identifiers

PMID38532722
PMCPMC11174057
OpenAlexW4388848084

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.