Evidence map›Paper›PMID 38532432›Full record

Trial reportTrials2024

Implementing and evaluating group interpersonal therapy for postnatal depression in Lebanon and Kenya-individually randomised superiority trial.

Peter Fonagy, Rabih El Chammay, Carol Ngunu, Manasi Kumar, Lena Verdeli, Elizabeth Allison, Ghida Anani, Pasco Fearon, Fouad Fouad, Zoe Hoare and 15 more

Open access · goldAbstract readMulticenter StudyRandomized Controlled TrialEquivalence Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 9 institutions in 4 countries.

Peter FonagyUniversity College London, London, UK. p.fonagy@ucl.ac.uk.ORCID http://orcid.org/0000-0003-0229-0091
Rabih El ChammayMinistry of Public Health Lebanon, Baabda, Lebanon.
Carol NgunuNairobi City County Government, Nairobi, Kenya.
Manasi KumarUniversity of Nairobi, Nairobi, Kenya.
Lena VerdeliColumbia University, New York, NY, USA.
Elizabeth AllisonUniversity College London, London, UK.
Ghida AnaniABAAD, Beirut, Lebanon.
Pasco FearonUniversity College London, London, UK.
Fouad FouadAmerican University of Beirut, Beirut, Lebanon.
Zoe HoareBangor University, Bangor, UK.
Lucina KoyioNairobi City County Government, Nairobi, Kenya.
Henrietta MooreUniversity College London, London, UK.
Andrew NyandigisiHealth Strat, Nairobi, Kenya.
Stephen PillingUniversity College London, London, UK.
Hannah SenderUniversity College London, London, UK.
Jolene SkordisUniversity College London, London, UK.
Rachel EvansBangor University, Bangor, UK.
Gerard Joseph Abou JaoudeUniversity College London, London, UK.
Beatrice MadegheUniversity of Nairobi, Nairobi, Kenya.
Sandra Pardi Arsen MaradianMinistry of Public Health Lebanon, Baabda, Lebanon.
Ciara O'DonnellUniversity College London, London, UK.
Elizabeth SimesUniversity College London, London, UK.
Alexandra TruscottUniversity College London, London, UK.
Grace Nduku WambuaUniversity of Nairobi, Nairobi, Kenya.
Obadia YatorUniversity of Nairobi, Nairobi, Kenya.
University College London · GBAnna Freud Centre · GBUniversity of Nairobi · KEBangor University · GBKenya School of Government · KEMinistry of Public Health · LBAmerican University of Beirut · LBColumbia University · USHealth Strat (Kenya) · KE

Funding

National Institute for Health and Care Research NIHR200851
6 · The paper itself

Abstract

backgroundDepression ranks as the foremost mental health concern among childbearing women. Within low- and middle-income countries (LMICs), between 20 and 25% of women encounter depression during pregnancy or soon after delivery. This condition impacts not only the mothers but also their offspring. Offspring of women suffering from postnatal depression (PND) exhibit suboptimal cognitive development and increased emotional and behavioural issues throughout their growth. This scenario becomes more pronounced in LMICs, where numerous adversities further jeopardise children's developmental progress. Despite antenatal services providing a pivotal platform to address women's mental health needs, PND treatment remains inaccessible in many LMICs. The World Health Organization advocates interpersonal psychotherapy (IPT) for treating depression. While research from high-income countries has established the efficacy of IPT and group-IPT (g-IPT) for PND, its effectiveness within the LMIC context and its potential benefits for child development remain uncharted. This study seeks to gauge the potency of g-IPT for women with PND in two LMICs.

methodsThis multi-site randomised controlled trial is a continuation of two preceding phases-conceptual mapping and a feasibility study executed in Lebanon and Kenya. Insights gleaned from these phases underpin this comprehensive RCT, which contrasts the efficacy and cost-effectiveness of high-quality standard care (HQ-SC) augmented with g-IPT against HQ-SC in isolation. The trial, characterised as an individually randomised superiority assessment, targets women with postnatal depression in Beirut, Lebanon, and Nairobi, Kenya. It aims to determine if culturally tailored g-IPT, administered within community settings in both countries, outperforms HQ-SC in influencing child developmental outcomes, maternal depression, and the quality of the mother-child bond. DISCUSSION: The SUMMIT trial, designed with pragmatism, possesses the magnitude to evaluate g-IPT within two LMIC frameworks. It seeks to enlighten policymakers, service commissioners, professionals, and users about g-IPT's potential to alleviate maternal PND and bolster child developmental outcomes in LMICs. Additionally, the trial will generate valuable data on the clinical and economic merits of high-quality standard care.

trial registrationISRCTN, ISRCTN15154316. Registered on 27 September 2023, https://doi.org/10.1186/ISRCTN15154316.

Indexed as

Depression, PostpartumPsychotherapy, GroupFemaleHumansKenyaLebanonWomen's HealthCultural adaptationEconomic evaluationGroup interpersonal therapyHigh-quality standard careInfant developmentLMICMultisite randomised controlled trialPost-natal depressionRandomised controlled trial

Identifiers

PMID38532432
PMCPMC10964704
OpenAlexW4393194017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.