ArticleBMC chemistry2024
Novel synthesis of new triazine sulfonamides with antitumor, anti-microbial and anti-SARS-CoV-2 activities.
Article in BMC chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 13 citations in OpenAlex.
- Synthesis and crystal structure of 4,6-di-amino-3-(prop-2-en-1-yl)-2-sulfanyl-idene-2,3-di-hydro-1,3,5-triazin-1-ium chloride.Acta crystallographica. Section E, Crystallographic communications · 2026Article
- Synthesis of 1,3,5-Triazine-Indole Conjugates as Broad-Spectrum Coronavirus Entry Inhibitors.ChemMedChem · 2026Article
- Synthesis and crystal structure of 1-{Acta crystallographica. Section E, Crystallographic communications · 2026Article
- Novel indole-based scaffolds: Design, synthesis, molecular modeling, and anti-proliferative evaluation.BMC chemistry · 2026Article
- Synthesis and crystal structure of 4,6-di-amino-1-cyclo-hexyl-1,3,5-triazine-2(1Acta crystallographica. Section E, Crystallographic communications · 2026Article
- New aspirin-chitosan conjugates as potential anti-Staphylococcus aureus agents.BMC chemistry · 2026Article
- Crystal structure of 4-chloro-Acta crystallographica. Section E, Crystallographic communications · 2025Article
- Synthetic strategies towards benzothiazole-based compounds of therapeutic potency: experimental, investigational and approved drugs.RSC advances · 2025Review
- Synthesis of heterocycle based carboxymethyl cellulose conjugates as novel anticancer agents targeting HCT116, MCF7, PC3 and A549 cells.Scientific reports · 2025Article
- Exploring the Potential of s-Triazine Derivatives as Novel Antifungal Agents: A Review.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Synthesis and crystal structure of 5-{(Acta crystallographica. Section E, Crystallographic communications · 2025Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Novel approach for synthesizing triazine sulfonamide derivatives is accomplished via reacting the sulfaguanidine derivatives with N-cyanodithioiminocarbonate. Further reaction of the novel triazine sulfonamide analogues with various secondary amines and anilines generated various substituted triazine sulfonamide analogues of promising broad-spectrum activities including anti-microbial, anti-tumor, and anti-viral properties. The in vitro anti-proliferative activities of most of the novel compounds were evaluated on the NCI-60 cell line panel. The antifungal and antibacterial activities of the compounds were also estimated. The anti-viral activity against SARS CoV-2 virus was performed using MTT cytotoxicity assay to evaluate the half-maximal cytotoxic concentration (CC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.