ArticleBMC plant biology2024
Integrative physiological, metabolomic, and transcriptomic analysis reveals the drought responses of two apple rootstock cultivars.
Article in BMC plant biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 12 citations in OpenAlex.
- Physiological-Biochemical Characteristics and Omics Landscape of Drought Tolerance inInternational journal of molecular sciences · 2026Article
- Genotype-Specific Biochemical Responses of Apple Trees to Repeated Drought-Rehydration Cycles.Plants (Basel, Switzerland) · 2026Article
- Integrated transcriptomic and metabolomic analyses reveal drought-response mechanisms in Suriana maritima from tropical coral islands.BMC plant biology · 2026Article
- Genome-Wide Identification of thePlants (Basel, Switzerland) · 2026Article
- Metabolomic insights into the mechanisms of chickpea milkvetch (Astragalus Cicer L.) response to salt stress.BMC plant biology · 2026Article
- Multi-Omics Analysis Reveals the Adaptive Responses ofBiology · 2026Article
- Screening olour mango half-sib progenies for dwarfing, vigour, and climate resilience.Scientific reports · 2025Article
- Widely targeted metabolic profiling reveals drought resistance mechanisms in alfalfa leaves.BMC plant biology · 2025Article
- TOR Mediates Stress Responses Through Global Regulation of Metabolome in Plants.International journal of molecular sciences · 2025Review
- Insights into the Metabolite Profiles of TwoBiomolecules · 2024Article
- Editorial: Using rootstocks in crops and fruit trees to mitigate the effects of climate change and abiotic stress.Frontiers in plant science · 2024Article
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9 authors at 1 institution in 1 country.
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Abstract
backgroundDrought is considered the main environmental factor restricting apple production and thus the development of the apple industry. Rootstocks play an important role in enhancing the drought tolerance of apple plants. Studies of the physiology have demonstrated that 'ZC9-3' is a strong drought-resistant rootstock, whereas 'Jizhen-2' is a weak drought-resistant rootstock. However, the metabolites in these two apple rootstock varieties that respond to drought stress have not yet been characterized, and the molecular mechanisms underlying their responses to drought stress remain unclear.
resultsIn this study, the physiological and molecular mechanisms underlying differences in the drought resistance of 'Jizhen-2' (drought-sensitive) and 'ZC9-3' (drought-resistant) apple rootstocks were explored. Under drought stress, the relative water content of the leaves was maintained at higher levels in 'ZC9-3' than in 'Jizhen-2', and the photosynthetic, antioxidant, and osmoregulatory capacities of 'ZC9-3' were stronger than those of 'Jizhen-2'. Metabolome analysis revealed a total of 95 and 156 differentially accumulated metabolites in 'Jizhen-2' and 'ZC9-3' under drought stress, respectively. The up-regulated metabolites in the two cultivars were mainly amino acids and derivatives. Transcriptome analysis revealed that there were more differentially expressed genes and transcription factors in 'ZC9-3' than in 'Jizhen-2' throughout the drought treatment. Metabolomic and transcriptomic analysis revealed that amino acid biosynthesis pathways play key roles in mediating drought resistance in apple rootstocks. A total of 13 metabolites, including L-α-aminoadipate, L-homoserine, L-threonine, L-isoleucine, L-valine, L-leucine, (2S)-2-isopropylmalate, anthranilate, L-tryptophan, L-phenylalanine, L-tyrosine, L-glutamate, and L-proline, play an important role in the difference in drought resistance between 'ZC9-3' and 'Jizhen-2'. In addition, 13 genes encoding O-acetylserine-(thiol)-lyase, S-adenosylmethionine synthetase, ketol-acid isomeroreductase, dihydroxyacid dehydratase, isopropylmalate isomerase, branched-chain aminotransferase, pyruvate kinase, 3-dehydroquinate dehydratase/shikimate 5-dehydrogenase, N-acetylglutamate-5-P-reductase, and pyrroline-5-carboxylate synthetase positively regulate the response of 'ZC9-3' to drought stress.
conclusionsThis study enhances our understanding of the response of apple rootstocks to drought stress at the physiological, metabolic, and transcriptional levels and provides key insights that will aid the cultivation of drought-resistant apple rootstock cultivars. Especially, it identifies key metabolites and genes underlying the drought resistance of apple rootstocks.
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