Evidence map›Paper›PMID 38532265›Full record

ArticleJournal of veterinary internal medicine

Clinical and magnetic resonance imaging findings in a French bulldog puppy with genetically confirmed congenital hypothyroidism.

Katia Sánchez González, Harry Warwick, Marius Conradie, Neringa Alisauskaite

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Katia Sánchez GonzálezNorthwest Veterinary Specialists, Runcorn, United Kingdom.ORCID https://orcid.org/0009-0008-7049-9827
Harry WarwickNorthwest Veterinary Specialists, Runcorn, United Kingdom.
Marius ConradieNorthwest Veterinary Specialists, Runcorn, United Kingdom.
Neringa AlisauskaiteNorthwest Veterinary Specialists, Runcorn, United Kingdom.ORCID https://orcid.org/0000-0003-1820-4717
Northwest Orthopaedic Specialists · US

Funding

Linnaeus Veterinary LimitedLinnaeus Veterinary supported the cost of the open access publication charges
6 · The paper itself

Abstract

A 7-month-old male French bulldog was referred for abnormal mentation and gait. Physical examination revealed a dome shaped calvarium and persistent bregmatic fontanelle. Neurological examination revealed proprioceptive ataxia, pelvic limb paraparesis and strabismus with moderate ventriculomegaly, thinning of the cerebral parenchyma, and widened cerebral sulci on magnetic resonance imaging. Masses were identified in the region of the thyroid, which appeared heterogeneous and hyperintense in T1-weighted and T2-weighted compared with the adjacent muscle signal masses were identified. Radiological diagnosis was hydrocephalus "ex vacuo" and goiter. Blood test revealed abnormally low total thyroxine (TT4), free thyroxine (FT4), and normal thyrotropin concentration. A diagnosis of congenital hypothyroidism was confirmed by positive genetic test for thyroid peroxidase mutation. Thyroxine supplementation treatment rapidly improved clinical signs.

Indexed as

Congenital HypothyroidismDog DiseasesMagnetic Resonance ImagingThyroxineAnimalsDogsHydrocephalusIodide PeroxidaseMaleIodide PeroxidaseThyroxineaxonopathycentral nervous systemgoiterhydrocephalushypomyelinationthyroid peroxidase mutation

Identifiers

PMID38532265
PMCPMC11099762
OpenAlexW4393229556

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.