Evidence map›Paper›PMID 38532155›Full record

ArticleActa neurochirurgica2024

Customised pre-operative cranioplasty to achieve maximal surgical resection of tumours with osseous involvement-a case series.

Swati Jain, Adel Helmy, Thomas Santarius, Nicola Owen, Kirsty Grieve, Peter Hutchinson, Ivan Timofeev

Abstract read
PubMed Publisher
In one paragraph

Article in Acta neurochirurgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Swati JainDivison of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 1TN, UK. sj657@cam.ac.uk.ORCID 0000-0002-4359-7260
Adel HelmyDivison of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 1TN, UK.
Thomas SantariusDivison of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 1TN, UK.
Nicola OwenDivison of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 1TN, UK.
Kirsty GrieveDivison of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 1TN, UK.
Peter HutchinsonDivison of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 1TN, UK.
Ivan TimofeevDivison of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 1TN, UK.
University of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSurgical resection with bony margins would be the treatment of choice for tumours with osseous involvement such as meningiomas and metastasis. By developing and designing pre-operative customised 3D modelled implants, the patient can undergo resection of meningioma and repair of bone defect in the same operation. We present a generalisable method for designing pre-operative cranioplasty in patients to repair the bone defect after the resection of tumours. MATERIALS AND

methodsWe included six patients who presented with a tumour that was associated with overlying bone involvement. They underwent placement of customised cranioplasty in the same setting. A customised implant using a pre-operative imaging was designed with a 2-cm margin to allow for any intra-operative requirements for extending the craniectomy.

resultsSix patients were evaluated in this case series. Four patients had meningiomas, 1 patient had metastatic breast cancer on final histology, and 1 patient was found to have an intra-osseous arteriovenous malformation. Craniectomy based on margins provided by a cutting guide was fashioned. After tumour removal and haemostasis, the cranioplasty was then placed. All patients recovered well post-operatively with satisfactory cosmetic results. No wound infection was reported in our series.

conclusionOur series demonstrate the feasibility of utilising pre-designed cranioplasty for meningiomas and other tumours with osseous involvement. Following strict infection protocols, minimal intra-operative handling/modification of the implant, and close follow-up has resulted in good cosmetic outcomes with no implant-related infections.

Indexed as

Decompressive CraniectomyMeningeal NeoplasmsMeningiomaPlastic Surgery ProceduresHumansPostoperative ComplicationsRetrospective StudiesSkullCranioplastyDecompressive craniectomyOsseous tumours

Identifiers

PMID38532155
OpenAlexW4393230648

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.