Evidence map›Paper›PMID 38531768›Full record

ArticleZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2024

Safety of early antiplatelet therapy for non-cardioembolic mild stroke patients with thrombocytopenia.

Dongjuan Xu, Huan Zhou, Mengmeng Hu, Yilei Shen, Hongfei Li, Lianyan Wei, Jing Xu, Zhuangzhuang Jiang, Xiaoli Shao, Zhenhua Xi and 3 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Dongjuan XuDepartment of Neurology, Affiliated Dongyang Hospital of Wenzhou Medical University, Jinhua 322100, Zhejiang Province, China. xdj0108@126.com.
Huan ZhouDepartment of Neurology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Mengmeng HuDepartment of Neurology, Affiliated Dongyang Hospital of Wenzhou Medical University, Jinhua 322100, Zhejiang Province, China.
Yilei ShenDepartment of Neurology, Affiliated Dongyang Hospital of Wenzhou Medical University, Jinhua 322100, Zhejiang Province, China.
Hongfei LiDepartment of Neurology, Affiliated Dongyang Hospital of Wenzhou Medical University, Jinhua 322100, Zhejiang Province, China.
Lianyan WeiDepartment of Neurology, Affiliated Dongyang Hospital of Wenzhou Medical University, Jinhua 322100, Zhejiang Province, China.
Jing XuDepartment of Neurology, Affiliated Dongyang Hospital of Wenzhou Medical University, Jinhua 322100, Zhejiang Province, China.
Zhuangzhuang JiangDepartment of Neurology, Affiliated Dongyang Hospital of Wenzhou Medical University, Jinhua 322100, Zhejiang Province, China.
Xiaoli ShaoDepartment of Neurology, the First People's Hospital of Chun'an, Hangzhou 311700, China.
Zhenhua XiDepartment of Neurology, Haiyan People's Hospital, Jiaxing 314300, Zhejiang Province, China.
Songbin HeDepartment of Neurology, Zhoushan Hospital, Zhoushan 316000, Zhejiang Province, China.
Min LouDepartment of Neurology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Shaofa KeDepartment of Neurology, Taizhou Hospital, Taizhou 318000, Zhejiang Province, China. kesf@enzemed.com.
Wenzhou Medical University · CNSecond Affiliated Hospital of Zhejiang University · CNFirst Hospital of Jiaxing · CNHangzhou First People's Hospital · CNZhoushan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the safety of early antiplatelet therapy for non-cardioembolic mild stroke patients with thrombocytopenia.

methodsData of acute ischemic stroke patients with baseline National Institutes of Health Stroke Scale (NIHSS) score ≤3 and a platelet count <100×10

resultsA total of 1868 non-cardioembolic mild stroke patients with thrombocytopenia were enrolled. Multivariate regression analyses showed that mono-antiplatelet therapy significantly increased the proportion of mRS score of 0-1 at discharge (

conclusionsFor non-cardioembolic mild stroke patients with thrombocytopenia, antiplatelet therapy remains a reasonable choice. Mono-antiplatelet therapy has the same efficiency as dual-antiplatelet therapy in neurological outcome improvement with lower risk of gastrointestinal bleeding.

Indexed as

Platelet Aggregation InhibitorsStrokeThrombocytopeniaAgedFemaleHumansIntracranial HemorrhagesIschemic StrokeMaleMiddle AgedPlatelet CountPlatelet Aggregation InhibitorsAntiplatelet therapyNon-cardioembolic strokeRetrospective studySafetyThrombocytopenia

Identifiers

PMID38531768
PMCPMC11057994
OpenAlexW4394758547

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.