Evidence map›Paper›PMID 38531668›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2024

Epidemiology and Treatment Outcomes of Tuberculosis With Chronic Hepatitis B Infection-California, 2016-2020.

J Bradford Bertumen, Lisa Pascopella, Emily Han, Rosie Glenn-Finer, Robert J Wong, Amit Chitnis, Devan Jaganath, Mirna Jewell, Prabhu Gounder, Sara McElroy and 2 more

Open access · greenAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. HBV/HCV coinfection and anti-tuberculosis drug-induced liver injury: from risk assessment and exploration of mechanisms to preventive considerations.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

J Bradford BertumenCenters for Disease Control and Prevention, Epidemic Intelligence Service, Atlanta, Georgia, USA.ORCID 0000-0002-1521-0276
Lisa PascopellaCalifornia Department of Public Health, Division of Communicable Disease Control, Richmond, California, USA.
Emily HanCalifornia Department of Public Health, Division of Communicable Disease Control, Richmond, California, USA.
Rosie Glenn-FinerCalifornia Department of Public Health, Division of Communicable Disease Control, Richmond, California, USA.
Robert J WongStanford University School of Medicine, Department of Medicine/Gastroenterology and Hepatology, Palo Alto, California, USA.
Amit ChitnisAlameda County Public Health Department, Tuberculosis Section/Division of Communicable Disease Control and Prevention, San Leandro, California, USA.
Devan JaganathUniversity of California, San Francisco School of Medicine, Center for Tuberculosis, San Francisco, California, USA.
Mirna JewellLos Angeles County Public Health Department, Communicable Disease Control and Prevention Division, Los Angeles, California, USA.
Prabhu GounderLos Angeles County Public Health Department, Communicable Disease Control and Prevention Division, Los Angeles, California, USA.
Sara McElroyCalifornia Department of Public Health, Division of Communicable Disease Control, Richmond, California, USA.
Lauren StockmanCalifornia Department of Public Health, Division of Communicable Disease Control, Richmond, California, USA.
Pennan BarryCalifornia Department of Public Health, Division of Communicable Disease Control, Richmond, California, USA.ORCID 0000-0003-2962-1890
California Department of Public Health · USLos Angeles County Department of Public Health · USAlameda County Public Health Department · USCenters for Disease Control and Prevention · USStanford University · USUniversity of California, San Francisco · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundImproved epidemiologic and treatment data for active tuberculosis (TB) with chronic hepatitis B virus (cHBV) infection might inform and encourage screening and vaccination programs focused on persons at risk of having both conditions.

methodsWe matched the California Department of Public Health TB registry during 2016-2020 to the cHBV registry using probabilistic matching algorithms. We used chi-square analysis to compare the characteristics of persons with TB and cHBV with those with TB only. We compared TB treatment outcomes between these groups using modified Poisson regression models. We calculated the time between reporting of TB and cHBV diagnoses for those with both conditions.

resultsWe identified 8435 persons with TB, including 316 (3.7%) with cHBV. Among persons with TB and cHBV, 256 (81.0%) were non-US-born Asian versus 4186 (51.6%) with TB only (P < .0001). End-stage renal disease (26 [8.2%] vs 322 [4.0%]; P < .001) and HIV (21 [6.7%] vs 247 [3.0%]; P = .02) were more frequent among those with TB and cHBV compared with those with TB only. Among those with both conditions, 35 (11.1%) had TB diagnosed >60 days before cHBV (median, 363 days) and 220 (69.6%) had TB diagnosed >60 days after cHBV (median, 3411 days).

conclusionsPersons with TB and cHBV were found more frequently in certain groups compared with TB only, and infrequently had their conditions diagnosed together. This highlights an opportunity to improve screening and treatment of TB and cHBV in those at high risk for coinfection.

Indexed as

Hepatitis B, ChronicTuberculosisAdolescentAdultAgedAntitubercular AgentsCaliforniaCoinfectionFemaleHIV InfectionsHumansMaleMiddle AgedRegistriesTreatment OutcomeYoung AdultAntitubercular Agentsdiagnostic timingepidemiologyhepatitis Btreatment outcomestuberculosis

Identifiers

PMID38531668
PMCPMC11493332
OpenAlexW4394766913

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.