Evidence map›Paper›PMID 38531620›Full record

ArticleRMD open2024

Incidence and clinical manifestations of giant cell arteritis in Spain: results of the ARTESER register.

Delia Fernández-Lozano, Iñigo Hernández-Rodríguez, Javier Narvaez, Marta Domínguez-Álvaro, Eugenio De Miguel, Maite Silva-Díaz, Joaquín María Belzunegui, Clara Moriano Morales, Julio Sánchez, Eva Galíndez-Agirregoikoa and 14 more

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
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  9. Role and potential ofFrontiers in medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 20 institutions in 2 countries.

Delia Fernández-LozanoRheumatology, Hospital Clinico Universitario de Valencia, Valencia, Spain.ORCID 0000-0001-9650-1296
Iñigo Hernández-RodríguezRheumatology, Complexo Hospitalario Universitario de Vigo, Vigo, Spain.
Javier NarvaezRheumatology, Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Spain.ORCID 0000-0002-1614-8064
Marta Domínguez-ÁlvaroResearch Unit, Sociedad Española de Reumatología, Madrid, Spain.ORCID 0000-0002-4057-5971
Eugenio De MiguelRheumatology, Hospital Universitario La Paz, Madrid, Spain.ORCID 0000-0001-5146-1964
Maite Silva-DíazRheumatology, Complexo Hospitalario Universitario A Coruna, A Coruna, Spain.ORCID 0000-0003-1904-011X
Joaquín María BelzuneguiRheumatology, Hospital of Donostia, San Sebastian, Spain.
Clara Moriano MoralesRheumatology, Complejo Asistencial Universitario de Leon, Leon, Spain.
Julio SánchezRheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain.
Eva Galíndez-AgirregoikoaRheumatology, Hospital Universitario Basurto, Bilbao, Spain.
Vicente AldarosoRheumatology, Complejo Hospitalario de Navarra, Pamplona, Spain.
Lydia AbasoloRheumatology, Hospital Clinico Universitario San Carlos, Madrid, Spain.
Javier LoriceraRheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain.ORCID 0000-0003-4754-0277
Noemi Garrido-PuñalRheumatology, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
Patricia Moya AlvaradoRheumatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.ORCID 0000-0001-8339-5420
Carmen LarenaRheumatology, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Vanessa Andrea NavarroRheumatology, Hospital Moises Broggi, Barcelona, Spain.
Joan CalvetRheumatology, Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA), Sabadell, Spain.ORCID 0000-0002-0888-5152
Ivette Casafont-SoléRheumatology, Hospital Germans Trias i Pujol, Barcelona, Spain.
Francisco Ortiz-SanjuánRheumatology, Hospital Politécnico y Universitario La Fe, Valencia, Spain.
Tarek Carlos Salman MonteRheumatology, Hospital del Mar, Barcelona, Spain.ORCID 0000-0002-4676-0174
Santos CastañedaRheumatology, Hospital Universitario de la Princesa. IIS-Princesa, Madrid, Spain.ORCID 0000-0002-7748-853X
Ricardo BlancoRheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain rblancovela@gmail.com.ORCID 0000-0003-2344-2285
ARTESER Project Collaborative Group
Center for Rheumatology · USMarqués de Valdecilla University Hospital · ESBellvitge University Hospital · ESBiogipuzkoa Health Research Institute · ESComplejo Hospitalario de Navarra · ESComplexo Hospitalario Universitario A Coruña · ESHospital Clínico San Carlos · ESHospital Clínico Universitario de Valencia · ESHospital de Basurto · ESHospital Del Mar · ESHospital de Sant Joan Despí Moisès Broggi · ESHospital de Sant Pau · ESHospital Universitari Germans Trias i Pujol · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario 12 De Octubre · ESHospital Universitario de La Princesa · ESHospital Universitario La Paz · ESHospital Universitario Virgen del Rocío · ESSociedad Española de Reumatología · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to estimate the incidence of giant cell arteritis (GCA) in Spain and to analyse its clinical manifestations, and distribution by age group, sex, geographical area and season.

methodsWe included all patients diagnosed with GCA between 1 June 2013 and 29 March 2019 at 26 hospitals of the National Health System. They had to be aged ≥50 years and have at least one positive results in an objective diagnostic test (biopsy or imaging techniques), meet 3/5 of the 1990 American College of Rheumatology classification criteria or have a clinical diagnosis based on the expert opinion of the physician in charge. We calculated incidence rate using Poisson regression and assessed the influence of age, sex, geographical area and season.

resultsWe identified 1675 cases of GCA with a mean age at diagnosis of 76.9±8.3 years. The annual incidence was estimated at 7.42 (95% CI 6.57 to 8.27) cases of GCA per 100 000 people ≥50 years with a peak for patients aged 80-84 years (23.06 (95% CI 20.89 to 25.4)). The incidence was greater in women (10.06 (95% CI 8.7 to 11.5)) than in men (4.83 (95% CI 3.8 to 5.9)). No significant differences were found between geographical distribution and incidence throughout the year (p=0.125). The phenotypes at diagnosis were cranial in 1091 patients, extracranial in 337 patients and mixed in 170 patients.

conclusionsThis is the first study to estimate the incidence of GCA in Spain at a national level. We found a predominance among women and during the ninth decade of life with no clear variability according to geographical area or seasons of the year.

Indexed as

Giant Cell ArteritisAgedAged, 80 and overBiopsyFemaleHumansIncidenceMaleSeasonsSpainepidemiologygiant cell arteritisincidencevasculitis

Identifiers

PMID38531620
PMCPMC10966818
OpenAlexW4393204480

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.