Evidence map›Paper›PMID 38531027›Full record

SynthesisEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2024

Continuous stellate ganglion block for ventricular arrhythmias: case series, systematic review, and differences from thoracic epidural anaesthesia.

Veronica Dusi, Filippo Angelini, Enrico Baldi, Antonio Toscano, Carol Gravinese, Simone Frea, Sara Compagnoni, Arianna Morena, Andrea Saglietto, Eleonora Balzani and 8 more

Open access · hybridAbstract readSystematic ReviewMulticenter Study
In one paragraph

Synthesis in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Percutaneous left stellate ganglion block for drug-refractory supraventricular arrhythmias in patients with advanced heart failure and cardiogenic shock: a pilot study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
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  11. The role of antiarrhythmic drugs and stellate ganglion block in the acute management of electrical storm.European heart journal supplements : journal of the European Society of Cardiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Veronica DusiCardiology, Department of Medical Sciences, University of Turin, Corso Dogliotti 14, 10126 Torino, Italy.ORCID 0000-0002-2290-3126
Filippo AngeliniDivision of Cardiology, Cardiovascular and Thoracic Department, 'Città della Salute e della Scienza' Hospital, Corso Bramante 88/90, 10126 Torino, Italy.ORCID 0000-0003-4711-0891
Enrico BaldiArrhythmia and Electrophysiology Unit, Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID 0000-0002-6360-224X
Antonio ToscanoDepartment of Anaesthesia, Critical Care and Emergency, 'Città della Salute e della Scienza' Hospital, Torino, Italy.ORCID 0000-0003-4587-4177
Carol GravineseDivision of Cardiology, Cardiovascular and Thoracic Department, 'Città della Salute e della Scienza' Hospital, Corso Bramante 88/90, 10126 Torino, Italy.ORCID 0009-0008-1453-9775
Simone FreaDivision of Cardiology, Cardiovascular and Thoracic Department, 'Città della Salute e della Scienza' Hospital, Corso Bramante 88/90, 10126 Torino, Italy.ORCID 0000-0002-2977-3299
Sara CompagnoniDepartment of Molecular Medicine, Section of Cardiology, University of Pavia, Viale Golgi 19, 27100 Pavia, Italy.ORCID 0000-0003-2289-5629
Arianna MorenaCardiology, Department of Medical Sciences, University of Turin, Corso Dogliotti 14, 10126 Torino, Italy.ORCID 0009-0004-7921-0234
Andrea SagliettoDivision of Cardiology, Cardiovascular and Thoracic Department, 'Città della Salute e della Scienza' Hospital, Corso Bramante 88/90, 10126 Torino, Italy.ORCID 0000-0001-9475-1507
Eleonora BalzaniDepartment of Surgical Sciences, University of Turin, Torino, Italy.ORCID 0000-0001-7837-4457
Matteo GiuntaDepartment of Anaesthesia, Critical Care and Emergency, 'Città della Salute e della Scienza' Hospital, Torino, Italy.ORCID 0000-0001-6380-221X
Andrea CostamagnaDepartment of Anaesthesia, Critical Care and Emergency, 'Città della Salute e della Scienza' Hospital, Torino, Italy.ORCID 0000-0002-0231-1545
Mauro RinaldiDepartment of Surgical Sciences, University of Turin, Torino, Italy.
Anna Chiara TrompeoDepartment of Anaesthesia, Critical Care and Emergency, 'Città della Salute e della Scienza' Hospital, Torino, Italy.
Roberto RordorfArrhythmia and Electrophysiology Unit, Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID 0000-0003-4111-1690
Matteo AnselminoCardiology, Department of Medical Sciences, University of Turin, Corso Dogliotti 14, 10126 Torino, Italy.ORCID 0000-0002-6311-4270
Simone SavastanoArrhythmia and Electrophysiology Unit, Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID 0000-0002-9789-6661
Gaetano Maria De FerrariCardiology, Department of Medical Sciences, University of Turin, Corso Dogliotti 14, 10126 Torino, Italy.ORCID 0000-0003-4940-0876
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITPoliclinico San Matteo Fondazione · ITUniversity of Pavia · ITUniversity of Turin · IT

Funding

European Union's Horizon-2020 research and innovation programme 945119
6 · The paper itself

Abstract

aimsPercutaneous stellate ganglion block (PSGB) through single-bolus injection and thoracic epidural anaesthesia (TEA) have been proposed for the acute management of refractory ventricular arrhythmias (VAs). However, data on continuous PSGB (C-PSGB) are scant. The aim of this study is to report our dual-centre experience with C-PSGB and to perform a systematic review on C-PSGB and TEA. METHODS AND

resultsConsecutive patients receiving C-PSGB at two centres were enrolled. The systematic literature review follows the latest Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. Our case series (26 patients, 88% male, 60 ± 16 years, all with advanced structural heart disease, left ventricular ejection fraction 23 ± 11%, 32 C-PSGBs performed, with a median duration of 3 days) shows that C-PSGB is feasible and safe and leads to complete VAs suppression in 59% and to overall clinical benefit in 94% of cases. Overall, 61 patients received 68 C-PSGBs and 22 TEA, with complete VA suppression in 63% of C-PSGBs (61% of patients). Most TEA procedures (55%) were performed on intubated patients, as opposed to 28% of C-PSGBs (P = 0.02); 63% of cases were on full anticoagulation at C-PSGB, none at TEA (P < 0.001). Ropivacaine and lidocaine were the most used drugs for C-PSGB, and the available data support a starting dose of 12 and 100 mg/h, respectively. No major complications occurred, yet TEA discontinuation rate due to side effects was higher than C-PSGB (18 vs. 1%, P = 0.01).

conclusionContinuous PSGB seems feasible, safe, and effective for the acute management of refractory VAs. The antiarrhythmic effect may be accomplished with less concerns for concomitant anticoagulation compared with TEA and with a lower side-effect related discontinuation rate.

Indexed as

Anesthesia, EpiduralAutonomic Nerve BlockStellate GanglionAgedAnesthetics, LocalFemaleHumansLidocaineMaleMiddle AgedTreatment OutcomeAnesthetics, LocalLidocaineCardiac arrestElectrical stormNeuromodulationRefractory ventricular arrhythmiasStellate ganglion blockThoracic epidural anaesthesia

Identifiers

PMID38531027
PMCPMC11020261
OpenAlexW4393237332

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.