Evidence map›Paper›PMID 38530893›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Feedforward and feedback mechanisms cooperatively regulate rapid experience-dependent response adaptation in a single thermosensory neuron type.

Tyler J Hill, Piali Sengupta

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

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  7. A multilayered gap junction network is essential for social decision-making.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tyler J HillDepartment of Biology, Brandeis University, Waltham, MA 02454.
Piali SenguptaDepartment of Biology, Brandeis University, Waltham, MA 02454.ORCID 0000-0001-7468-0035
Brandeis University · US

Funding

Mechanisms of sensory neuron morphological diversification, signaling, and functional plasticityR35GM122463 · NIGMS · BRANDEIS UNIVERSITY · PI Piali Sengupta · 2017 to 2026
$7.7M
NIGMS NIH HHS R35 GM122463
6 · The paper itself

Abstract

Sensory adaptation allows neurons to adjust their sensitivity and responses based on recent experience. The mechanisms that mediate continuous adaptation to stimulus history over seconds- to hours-long timescales, and whether these mechanisms can operate within a single sensory neuron type, are unclear. The single pair of AFD thermosensory neurons in

Indexed as

Caenorhabditis elegans ProteinsAnimalsCaenorhabditis elegansCalciumFeedbackSensory Receptor CellsCaenorhabditis elegans ProteinsCalciumadaptationC. eleganscGMP-gated channelreceptor guanylyl cyclasethermosensation

Identifiers

PMID38530893
PMCPMC10998601
OpenAlexW4393187087

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.