ArticleGenome biology and evolution2024
Identification of Parthenogenesis-Inducing Effector Proteins in Wolbachia.
Article in Genome biology and evolution, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 27 citations in OpenAlex.
- Three decades of analyzing Wolbachia bacterial endosymbionts in arthropods: Trends and gaps.Parasitology research · 2026Review
- Article
- Identification of twomBio · 2026Article
- Genomics and reproductive biology of Leptopilina malgretoutensis (sp. nov.): an asexual parasitoid of Caribbean Drosophila.Genetics · 2026Article
- Extensive mobilome dynamics in a widespread endosymbiont: long read metagenomics reveal dimeric plasmids and highly fragmented prophages in Wolbachia from Culex pipiens.Research square · 2026Article
- Curing Parthenogenesis-Inducing (PI)Biology · 2026Article
- Gametophytic Apomixis: An Introduction.Methods in molecular biology (Clifton, N.J.) · 2026Review
- Article
- A co-speciation dilemma and a lifestyle transition with genomic consequences in Wolbachia of Neotropical Drosophila.BMC genomics · 2025Article
- Comparative Genomics of the Endosymbiont Cardinium Causing Reproductive Manipulation in Encarsia Parasitoid Wasps.MicrobiologyOpen · 2025Article
- Endosymbionts interacting with sex-determining genes and processes.Current opinion in insect science · 2025Review
- Single-cell genome analysis of a feminizingMicrobial genomics · 2025Article
- Evolutionary Diversification and Functions of the Candidate Male Killing Gene wmk.Genome biology and evolution · 2025Article
- Diversity and spread of cytoplasmic incompatibility genes among maternally inherited symbionts.PLoS genetics · 2025Article
- A reference genome for Trichogramma kaykai: a tiny desert-dwelling parasitoid wasp with competing sex-ratio distorters.G3 (Bethesda, Md.) · 2025Article
- Wolbachia Feminises a Spider Host With Assistance From Co-Infecting Symbionts.Environmental microbiology · 2025Article
- Article
- Elucidating the Molecular Mechanisms of Sex Ratio Distortion Mediated by Cytoplasmic Symbionts.Genome biology and evolution · 2025Review
- Alien spiders in a palm house with the first report of parthenogenetic Triaeris stenaspis (Araneae: Oonopidae) infected by Wolbachia from new supergroup X.Scientific reports · 2025Article
- The ecology, evolution, and physiology of Cardinium: a widespread heritable endosymbiont of invertebrates.FEMS microbiology reviews · 2025Review
Corrections and comments
- Update of
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Bacteria in the genus Wolbachia have evolved numerous strategies to manipulate arthropod sex, including the conversion of would-be male offspring to asexually reproducing females. This so-called "parthenogenesis induction" phenotype can be found in a number of Wolbachia strains that infect arthropods with haplodiploid sex determination systems, including parasitoid wasps. Despite the discovery of microbe-mediated parthenogenesis more than 30 yr ago, the underlying genetic mechanisms have remained elusive. We used a suite of genomic, computational, and molecular tools to identify and characterize two proteins that are uniquely found in parthenogenesis-inducing Wolbachia and have strong signatures of host-associated bacterial effector proteins. These putative parthenogenesis-inducing proteins have structural homology to eukaryotic protein domains including nucleoporins, the key insect sex determining factor Transformer, and a eukaryotic-like serine-threonine kinase with leucine-rich repeats. Furthermore, these proteins significantly impact eukaryotic cell biology in the model Saccharomyces cerevisiae. We suggest that these proteins are parthenogenesis-inducing factors and our results indicate that this would be made possible by a novel mechanism of bacterial-host interaction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.