Evidence map›Paper›PMID 38530584›Full record

ReviewInternational urology and nephrology2024

ROC curve analysis: a useful statistic multi-tool in the research of nephrology.

Stefanos Roumeliotis, Juul Schurgers, Dimitrios G Tsalikakis, Graziella D'Arrigo, Mercedes Gori, Annalisa Pitino, Daniela Leonardis, Giovanni Tripepi, Vassilios Liakopoulos

Abstract readReview
In one paragraph

Review in International urology and nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Observational
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  10. AnCurrent drug targets · 2026
    Article
  11. An Operational Status Assessment Model for SFSensors (Basel, Switzerland) · 2025
    Article
  12. Development of a Machine Learning Tool for Home-Based Assessment of Periodontitis.medRxiv : the preprint server for health sciences · 2025
    Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stefanos Roumeliotis2nd Department of Nephrology, Medical School, AHEPA Hospital, Aristotle University of Thessaloniki, 54636, Thessaloniki, Greece.
Juul Schurgers *2nd Department of Nephrology, Medical School, AHEPA Hospital, Aristotle University of Thessaloniki, 54636, Thessaloniki, Greece.
Dimitrios G TsalikakisDepartment of Electrical and Computer Engineering, University of Western Macedonia, Kozani, Greece.
Graziella D'ArrigoInstitute of Clinical Physiology (IFC), National Research Council (CNR), 89124, Reggio Calabria, Italy.
Mercedes GoriInstitute of Clinical Physiology (IFC), National Research Council (CNR), 00100, Rome, Italy.
Annalisa PitinoInstitute of Clinical Physiology (IFC), National Research Council (CNR), 89124, Reggio Calabria, Italy.
Daniela LeonardisInstitute of Clinical Physiology (IFC), National Research Council (CNR), 89124, Reggio Calabria, Italy.
Giovanni Tripepi *Institute of Clinical Physiology (IFC), National Research Council (CNR), 89124, Reggio Calabria, Italy.
Vassilios Liakopoulos *2nd Department of Nephrology, Medical School, AHEPA Hospital, Aristotle University of Thessaloniki, 54636, Thessaloniki, Greece. liakopul@otenet.gr.ORCID http://orcid.org/0000-0002-7564-2724

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past decade, scientific research in the area of Nephrology has focused on evaluating the clinical utility and performance of various biomarkers for diagnosis, risk stratification and prognosis. Before implementing a biomarker in everyday clinical practice for screening a specific disease context, specific statistic measures are necessary to evaluate the diagnostic accuracy and performance of this biomarker. Receiver Operating Characteristic (ROC) Curve analysis is an important statistical method used to estimate the discriminatory performance of a novel diagnostic test, identify the optimal cut-off value for a test that maximizes sensitivity and specificity, and evaluate the predictive value of a certain biomarker or risk, prediction score. Herein, through practical examples, we aim to present a simple methodological approach to explain in detail the principles and applications of ROC curve analysis in the field of nephrology pertaining diagnosis and prognosis.

Indexed as

NephrologyROC CurveBiomarkersBiomedical ResearchHumansKidney DiseasesPrognosisBiomarkersArea under the curveDiagnostic test,Discriminatory abilityReceiver operator characteristic curveSensitivitySpecificity

Identifiers

PMID38530584
PMCPMC11266376

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.