Evidence map›Paper›PMID 38530563›Full record

ArticleJournal of fluorescence2025

Exploring the Gamma-Ray Enhanced NIR-Luminescence and Cytotoxic Potential of Lanthanide-Naphthalene Dicarboxylate based Metal-Organic Frameworks.

Podilapu Atchutha Rao, Harihara Padhy, Krishanu Bandyopadhyay, Adapaka Venkateswara Rao, Ravikumar Ganta, Samatha Bevara, Bheeshma Pratap Singh, Bhavani Kundrapu, Satyen Saha, RamaRao Malla and 1 more

Abstract read
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Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Podilapu Atchutha RaoDepartment of Chemistry, GITAM School of Science, GITAM (Deemed to be University), Visakhapatnam, AP, 530045, India.
Harihara PadhyDepartment of Chemistry, GITAM School of Science, GITAM (Deemed to be University), Visakhapatnam, AP, 530045, India. hariharapadhy@gmail.com.
Krishanu BandyopadhyayDepartment of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, 221005, India.
Adapaka Venkateswara RaoDepartment of Chemistry, GITAM School of Science, GITAM (Deemed to be University), Visakhapatnam, AP, 530045, India.
Ravikumar GantaDepartment of Chemistry, GITAM School of Science, GITAM (Deemed to be University), Visakhapatnam, AP, 530045, India.
Samatha BevaraDepartment of Chemistry, GITAM School of Science, GITAM (Deemed to be University), Visakhapatnam, AP, 530045, India.
Bheeshma Pratap SinghDepartment of Physics, GITAM School of Science, GITAM (Deemed to be University), Visakhapatnam, AP, 530045, India.
Bhavani KundrapuCancer Biology Laboratory, Department of Biochemistry and Bioinformatics, GITAM School of Science, GITAM (Deemed to be University), Visakhapatnam, 530045, Andhra Pradesh, India.
Satyen SahaDepartment of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, 221005, India.
RamaRao MallaCancer Biology Laboratory, Department of Biochemistry and Bioinformatics, GITAM School of Science, GITAM (Deemed to be University), Visakhapatnam, 530045, Andhra Pradesh, India.
Saratchandra Babu MukkamalaDepartment of Chemistry, Central Tribal University of Andhra Pradesh, Vizianagaram, 535003, AP, India. saratchandra@ctuap.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this investigation, we explore the integration of lanthanides into Metal-Organic Frameworks (MOFs) to enable Near-Infrared (NIR) emission. Specifically, we focus on Lanthanide-Naphthalene Dicarboxylate based MOFs (Ln-MOFs), incorporating elements such as Praseodymium (Pr), Samarium (Sm), Dysprosium (Dy), and Erbium (Er). The synthesis of Ln-MOFs is achieved via the hydrothermal method. The structure, morphology, thermal stability, and luminescence properties of synthesized Ln-MOFs have been evaluated through different characterization techniques. Upon photoexcitation at 350 nm, Ln-MOFs show the emission in the Visible and NIR region. Further, the luminescence intensity of Ln-MOFs enhanced by 2-3 folds in the visible region and 6-8 folds in NIR region after exposing to Gamma irradiation at 150 kGy. Cytotoxic effect on the viability of MDA-MB 231 and MDA-MB 468 Triple negative breast cancer (TNBC) cells was evaluated by MTT assay. The results revealed that among all synthesized MOFs, Pr-MOF exhibited an aggressive cytotoxic effect. Additionally, analysis of phase-contrast microscopy data indicates that Pr-MOF induces alterations in the morphology of both MDA-MB 231 and MDA-MB 468 TNBC cells when compared to untreated controls. The findings in this study reveal the utilization of Ln-MOFs for studying cytotoxicity and highlight their ability to enhance near-infrared (NIR) emission when exposed to gamma radiation.

Indexed as

Antineoplastic AgentsCarboxylic AcidsGamma RaysInfrared RaysLanthanoid Series ElementsLuminescenceMetal-Organic FrameworksNaphthalenesCell Line, TumorCell ProliferationCell SurvivalHumansAntineoplastic AgentsCarboxylic AcidsLanthanoid Series ElementsMetal-Organic FrameworksnaphthaleneNaphthalenesCytotoxicityGamma radiationLanthanide metalsLuminescenceMetal–organic frameworksNear-IR emission

Identifiers

PMID38530563

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.