Evidence map›Paper›PMID 38530220›Full record

ArticleBioanalysis2024

Pharmacokinetics and apparent Michaelis constant for metabolite conversion of sorafenib in healthy and hepatocellular carcinoma-bearing rats.

Hongxin Cai, Xiaoyue Du, Yufeng Deng, Dejian Cao, Lele Wang, Zhiguo Wu, Xianchao Zhang, Jinbiao Xu, Baogang Xie

Open access · greenAbstract read
In one paragraph

Article in Bioanalysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hongxin CaiSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310000, China.
Xiaoyue DuSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310000, China.
Yufeng DengSchool of Pharmaceutical Science, Nanchang University, Nanchang, 330001, China.
Dejian CaoMedical College of Jiaxing University, Key Laboratory of Medical Electronics & Digital Health of Zhejiang Province, Jiaxing University, Jiaxing, 314001, China.
Lele WangMedical College of Jiaxing University, Key Laboratory of Medical Electronics & Digital Health of Zhejiang Province, Jiaxing University, Jiaxing, 314001, China.
Zhiguo WuSchool of Pharmaceutical Science, Nanchang University, Nanchang, 330001, China.
Xianchao ZhangMedical College of Jiaxing University, Key Laboratory of Medical Electronics & Digital Health of Zhejiang Province, Jiaxing University, Jiaxing, 314001, China.
Jinbiao XuMedical College of Jiaxing University, Key Laboratory of Medical Electronics & Digital Health of Zhejiang Province, Jiaxing University, Jiaxing, 314001, China.
Baogang XieSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310000, China.ORCID 0000-0002-0685-1346
Jiaxing University · CNZhejiang Chinese Medical University · CNNanchang University · CN

Funding

National Natural Science Foundation of China 82374096Zhejiang Chinese Medical University Postgraduate Scientific Research Fund Project 2022YKJ24
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsNiacinamidePhenylurea CompoundsSorafenibAnimalsAntineoplastic AgentsChromatography, High Pressure LiquidMaleMass SpectrometryRatsRats, Sprague-DawleyAntineoplastic AgentsNiacinamidePhenylurea CompoundsSorafenibhepatocellular carcinomametabolismMichaelis constantpharmacokineticssorafenib

Identifiers

PMID38530220
PMCPMC11216244
OpenAlexW4393181967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.