Evidence map›Paper›PMID 38529944›Full record

ArticleMicrobial genomics2024

Optimising machine learning prediction of minimum inhibitory concentrations in

Gherard Batisti Biffignandi, Leonid Chindelevitch, Marta Corbella, Edward J Feil, Davide Sassera, John A Lees

Open access · goldAbstract read
In one paragraph

Article in Microbial genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Gherard Batisti BiffignandiDepartment of Biology and Biotechnology, University of Pavia, Pavia, Italy.
Leonid ChindelevitchMRC Centre for Global Infectious Disease Analysis, Imperial College, London, England, UK.
Marta CorbellaMicrobiology and Virology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Edward J FeilThe Milner Centre for Evolution, Department of Life Sciences, University of Bath, Bath, UK.
Davide SasseraDepartment of Biology and Biotechnology, University of Pavia, Pavia, Italy.
John A LeesEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, UK.
European Bioinformatics Institute · GBImperial College London · GBPoliclinico San Matteo Fondazione · ITUniversity of Bath · GBUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimum Inhibitory Concentrations (MICs) are the gold standard for quantitatively measuring antibiotic resistance. However, lab-based MIC determination can be time-consuming and suffers from low reproducibility, and interpretation as sensitive or resistant relies on guidelines which change over time. Genome sequencing and machine learning promise to allow

Indexed as

Anti-Bacterial AgentsKlebsiella pneumoniaeMachine LearningMicrobial Sensitivity TestsReproducibility of ResultsAnti-Bacterial AgentsAMRantibiotic resistancebacterial genomicsGWASKlebsiella pneumoniaemachine learningMIC

Identifiers

PMID38529944
PMCPMC10995625
OpenAlexW4393192460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.