Evidence map›Paper›PMID 38529508›Full record

ArticlebioRxiv : the preprint server for biology2024

The modification landscape of

Mariana D Mandler, Siddhardha S Maligireddy, Wilfried M Guiblet, Christina M Fitzsimmons, Kayla S McDonald, Delayna L Warrell, Pedro J Batista

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Mariana D MandlerLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health.ORCID 0000-0003-1609-6871
Siddhardha S MaligireddyLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health.ORCID 0000-0003-1143-7788
Wilfried M GuibletLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health.
Christina M FitzsimmonsLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health.ORCID 0000-0002-6743-2671
Kayla S McDonaldLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health.
Delayna L WarrellLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institues of Health.
Pedro J BatistaLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health.ORCID 0000-0003-1055-2354
National Institutes of Health · USCenter for Cancer Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA modifications have a substantial impact on tRNA function, with modifications in the anticodon loop contributing to translational fidelity and modifications in the tRNA core impacting structural stability. In bacteria, tRNA modifications are crucial for responding to stress and regulating the expression of virulence factors. Although tRNA modifications are well-characterized in a few model organisms, our knowledge of tRNA modifications in human pathogens, such as

Indexed as

4-thiouridineacp3UP. aeruginosatRNAtRNA modificationvariable region

Identifiers

PMID38529508
PMCPMC10962704
OpenAlexW4392189513

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.