Evidence map›Paper›PMID 38529497›Full record

ArticlebioRxiv : the preprint server for biology2024

Development of novel tools for dissection of central versus peripheral dopamine D

Alessandro Bonifazi, Michael Ellenberger, Zachary J Farino, Despoina Aslanoglou, Rana Rais, Sandra Pereira, José O Mantilla-Rivas, Comfort A Boateng, Amy J Eshleman, Aaron Janowsky and 5 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Alessandro BonifaziMedicinal Chemistry Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA.ORCID 0000-0002-7306-0114
Michael EllenbergerMedicinal Chemistry Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA.
Zachary J FarinoDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-7168-306X
Despoina AslanoglouDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-8444-1385
Rana RaisDepartment of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-4059-2453
Sandra PereiraCentre for Addiction and Mental Health, Toronto, ON, Canada.
José O Mantilla-RivasDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-3455-2730
Comfort A BoatengMedicinal Chemistry Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA.ORCID 0000-0003-1907-431X
Amy J EshlemanResearch Service, VA Portland Health Care System, Portland, Oregon, USA.ORCID 0000-0001-7030-557X
Aaron JanowskyResearch Service, VA Portland Health Care System, Portland, Oregon, USA.ORCID 0000-0002-9221-3841
Margaret K HahnCentre for Addiction and Mental Health, Toronto, ON, Canada.ORCID 0000-0001-8884-9946
Gary J SchwartzThe Fleischer Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0003-0446-5553
Barbara S SlusherDepartment of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-9814-4157
Amy Hauck NewmanMedicinal Chemistry Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA.ORCID 0000-0001-9065-4072
Zachary FreybergDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0001-6460-0118
National Institutes of Health · USUniversity of Pittsburgh · USCentre for Addiction and Mental Health · CAJohns Hopkins University · USOregon Health & Science University · USAlbert Einstein College of Medicine · US

Funding

NOVEL DOPAMINE D3 RECEPTOR LIGANDSZ01DA000424 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI NEWMAN, AMY HAUCK · 1999 to 2008
$1.8M
Development of High-Affinity and Selective Ligands as a Pharmacological Tool for the Dopamine D4 Receptor (D4R) Subtype VariantsDP1DA058385 · NIDA · HIGH POINT UNIVERSITY · PI Comfort Ahenkan Boateng · 2023 to 2026
$1.8M
Novel dopaminergic mechanisms of islet hormone secretion and antipsychotic drug-induced metabolic disturbancesR01DK124219 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FREYBERG, ZACHARY · 2021 to 2023
$1.2M
Revealing Novel Mechanisms of Amphetamine Action in a Drosophila ModelK08DA031241 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI FREYBERG, ZACHARY · 2011 to 2015
$931k
Trace amine receptor-mediated methamphetamine response in brainI01BX002758 · VA · PORTLAND VA MEDICAL CENTER · PI JANOWSKY, AARON J. · 2016 to 2019
–
BLRD Senior Research Career Scientist Award ApplicationIK6BX005754 · VA · PORTLAND VA MEDICAL CENTER · PI JANOWSKY, AARON J. · 2022 to 2024
–
BLRD VA I01 BX002758BLRD VA IK6 BX005754Intramural NIH HHS Z01 DA000424NIDA NIH HHS DP1 DA058385NIDA NIH HHS K08 DA031241NIDDK NIH HHS R01 DK124219
6 · The paper itself

Abstract

Dopamine (DA) D

Indexed as

braindiabetesDopaminedopamine receptorsdysglycemiainsulinpancreas

Identifiers

PMID38529497
PMCPMC10962703
OpenAlexW4392189893

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.