Evidence map›Paper›PMID 38529356›Full record

ArticleTransplantation direct2024

Frailty Changes After Liver Transplantation. Results From a Spanish Multicenter Prospective Cohort Study.

Lorena Puchades, Julia Herreras, Maria Àngels Cebrià I Iranzo, Érick Reyes, Gonzalo Crespo, Manuel Rodríguez-Perálvarez, Luis Cortés, Trinidad Serrano, Ainhoa Fernández-Yunquera, Eva Montalvá and 1 more

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Lorena PuchadesHepatology and Liver Transplantation Group, Medical Research Institute Hospital La Fe, Valencia, Spain.
Julia HerrerasHepatology and Liver Transplantation Group, Medical Research Institute Hospital La Fe, Valencia, Spain.
Maria Àngels Cebrià I IranzoMedical Research Institute Hospital La Fe, Hepatology and Liver Transplantation Group, Valencia, Spain.
Érick ReyesLiver Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Gonzalo CrespoCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Valencia, Spain.
Manuel Rodríguez-PerálvarezCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Valencia, Spain.
Luis CortésLiver Transplantation Unit, Department of Gastroenterology, University Hospital Lozano Blesa, Zaragoza, Spain.
Trinidad SerranoCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Valencia, Spain.
Ainhoa Fernández-YunqueraCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Valencia, Spain.
Eva MontalváHepatology and Liver Transplantation Group, Medical Research Institute Hospital La Fe, Valencia, Spain.
Marina BerenguerHepatology and Liver Transplantation Group, Medical Research Institute Hospital La Fe, Valencia, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas · ESUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Until now, there has been limited evidence, primarily from US cohorts, focusing on frailty as a patient-oriented outcome after liver transplantation (LT). Our study aimed to explore the relationship between pre- and post-LT frailty in a multicenter European cohort of outpatients with cirrhosis undergoing LT. Methods: We conducted a prospective analysis of data from 180 LT recipients recruited between 2018 and 2020 from 5 Spanish centers. Participants underwent objective and subjective frailty assessments using the Liver Frailty Index (LFI) and the Subjective Clinician Assessment (SCA) pretransplant and at 3- and/or 6-mo posttransplant. Results: The median pretransplant LFI was 3.9, showing minimal change at 3 mo (3.8; Conclusion: In our European cohort, incomplete improvement of physical frailty was observed, with <20% achieving robust physical condition within 6-mo post-LT. The pretransplant LFI strongly predicted posttransplant frailty. As the SCA tends to overestimate physical function, we recommend using both subjective and objective tools for frailty assessment in LT candidates and recipients.

Identifiers

PMID38529356
PMCPMC10962876
OpenAlexW4393075402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.