ReviewAnnals of joint2022
Classification and management options for prosthetic joint infection.
Review in Annals of joint, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- The effect of extended postoperative oral antibiotic prophylaxis on the reinfection risk following two-stage exchange arthroplasty for hip and knee periprosthetic joint infection: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Diagnostic value of magnetic resonance imaging for patients with periprosthetic joint infection: a systematic review.BMC musculoskeletal disorders · 2023Pooled it
- From Trends to Insights: Management of Periprosthetic Joint Infections in the Past Decade in The Netherlands.Microorganisms · 2026Article
- Optimizing the management of periprosthetic infections with artificial intelligence: current evidence and future directions.EFORT open reviews · 2026Review
- [American journal of nuclear medicine and molecular imaging · 2026Review
- Case Report: Report of 2 cases of periprosthetic joint infection caused by Brucella after joint replacement and literature review.Frontiers in surgery · 2026Article
- Extensive Femoral Bone Loss Following Two-Stage Periprosthetic Joint Infection Treatment: Persistent Challenges in Proximal Femoral Replacement.Arthroplasty today · 2025Article
- Microfluidic and lab-on-a-chip devices for detection and diagnosis of periprosthetic joint infections.Biomedical microdevices · 2025Review
- High sensitivity and enhanced antibiotic stewardship of the BioFire Joint Infection Panel in acute, but not chronic, prosthetic joint infection of the knee.Microbiology spectrum · 2025Article
- Early and Accurate Pathogen Identification Based on mNGS: Key to Timely Therapy for Mycoplasma Prosthetic Joint Infection.Orthopaedic surgery · 2025Article
- Diagnosis of Prosthetic Joint Infection of Hips and Knees-One Size Does Not Fit All.Open forum infectious diseases · 2025Article
- Microbiological profile of prosthetic joint infections in orthopedic oncology: a comparison with conventional joint arthroplasty.Journal of bone and joint infection · 2025Article
- Article
- The Efficacy of Antibiotic-Loaded Calcium Sulfate Beads (Stimulan) in Patients with Hip Arthroplasty Infections.Journal of clinical medicine · 2024Article
- Microbiology of Prosthetic Joint Infections: A Retrospective Study of an Italian Orthopaedic Hospital.Antibiotics (Basel, Switzerland) · 2024Article
- What Is the Rate of Antimicrobial Resistance of a Prosthetic Joint Infection in a Major Orthopaedic Centre?Antibiotics (Basel, Switzerland) · 2024Article
- Emerging Technologies in Diagnosing Periprosthetic Joint Infections.Indian journal of orthopaedics · 2023Review
- Predicting the Exception-CRP and Primary Hip Arthroplasty.Journal of clinical medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periprosthetic joint infection (PJI) is one of the major complications following arthroplasty implantation. Management of PJIs is a challenge for surgeons and various classification systems have been introduced, which consider variables such as onset of symptoms, pathogenesis and clinical manifestation. In an attempt to overcome the shortcomings which may limit their usefulness in borderline cases, a new classification system focusing on the topography of the infectious process has been proposed. This theory relies on the identification of the exact location of the bacterial colonization thus allowing to decide between a conservative or a more radical intervention irrespectively of the timing. The use of nuclear medicine device like radiolabelled white blood cells (WBC) scan could lead the path in identifying pathogenetic processes and their exact location thus guiding orthopaedic surgeons to the most appropriate diagnosis and treatment options. Currently management relies on debridement, antibiotics and implant retention (DAIR), which is traditionally performed at early stages, 1- or 2-stage revision arthroplasty which is commonly limited to chronic cases. Reports have demonstrated similar rates of infection recurrence following one and two-stage revisions, and the use of one-stage revision surgery is gaining popularity. More recently, satisfying results following partial implant retention during revision total arthroplasty for septic failures have been reported. In addition, in severe cases, definitive articulating antibiotic spacer, excision arthroplasty, arthrodesis or amputation can be performed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.