Evidence map›Paper›PMID 38529072›Full record

ArticleFrontiers in pain research (Lausanne, Switzerland)2024

Evaluation of physical variables, thermal nociceptive threshold testing and pharmacokinetics during placement of transdermal buprenorphine matrix-type patch in healthy adult horses.

Vaidehi V Paranjape, Heather K Knych, Londa J Berghaus, Jessica Cathcart, Shyla Giancola, Hannah Craig, Caroline James, Siddharth Saksena, Rachel A Reed

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pain research (Lausanne, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Vaidehi V ParanjapeDepartment of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States.
Heather K KnychK. L. Maddy Equine Analytical Pharmacology Laboratory, School of Veterinary Medicine, University of California-Davis, Davis, CA, United States.
Londa J BerghausDepartment of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, United States.
Jessica CathcartDepartment of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, United States.
Shyla GiancolaDepartment of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, United States.
Hannah CraigDepartment of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, United States.
Caroline JamesDepartment of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, United States.
Siddharth SaksenaDepartment of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States.
Rachel A ReedDepartment of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, United States.
University of Georgia · USVirginia Tech · USUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Matrix type transdermal buprenorphine patches have not been investigated in horses and may provide an effective means of providing continuous pain control for extended period and eliminating venous catheterization. Objective: Assessment of the physiological variables (heart rate, respiratory rate, body temperature) and thermal nociceptive threshold testing, and describing the pharmacokinetic profile of transdermal buprenorphine matrix-type patch (20 μg h Study design: Randomised experimental study with a Latin-square design. Methods: Six adult healthy horses received each of the three treatments with a minimum 10 day washout period. BUP0 horses did not receive a patch (control). BUP20 horses received one patch (20 μg h Results: Between the three groups, there was no change in physiological variables across timepoints as compared to baseline ( Conclusions: 20 μg h

Indexed as

analgesiaequineopioidspainpain-freepharmacologythermal antinociception

Identifiers

PMID38529072
PMCPMC10961409
OpenAlexW4392653112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.