Evidence map›Paper›PMID 38529070›Full record

ArticleTherapeutic advances in gastroenterology2024

Retrospective subgroup analysis of fecal microbiota, live-jslm (REBYOTA

Whitfield L Knapple, David S Yoho, Alexander Sheh, Joan Thul, Paul Feuerstadt

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Newer Therapeutics to Selectively KillInfectious disease reports · 2026
    Review
  3. Safety and effectiveness of fecal microbiota, live-jslm (REBYOTATherapeutic advances in gastroenterology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Whitfield L KnappleArkansas Gastroenterology, 3401 Springhill Drive #400, North Little Rock, AR 72117, USA.ORCID https://orcid.org/0009-0007-4081-3304
David S YohoMid-Atlantic Permanente Medical Group, Springfield, VA, USA.
Alexander ShehRebiotix, Inc., a Ferring Company, Roseville, MN, USA.
Joan ThulFerring Pharmaceuticals, Inc., Parsippany, NJ, USA.
Paul FeuerstadtYale University School of Medicine, New Haven, CT, USA.ORCID https://orcid.org/0000-0002-7643-9576
Arkansas Department of Agriculture · USFerring Pharmaceuticals (United States) · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fecal microbiota, live-jslm (RBL; REBYOTA Objectives: Evaluate the safety and efficacy of RBL administration Design: Retrospective analysis of electronic medical records of participants administered RBL Methods: The number of participants with treatment and/or procedure-emergent adverse events (TEAEs) was evaluated. Treatment success and sustained clinical response, defined as the absence of CDI recurrence within 8 weeks and 6 months, respectively, were evaluated. Results: TEAEs were experienced by 75% (6/8) of participants; most were mild to moderate in severity, and none due to RBL or its administration. Most participants had treatment success (80%; 8/10); 75% (6/8) had sustained clinical response. Conclusion: Real-world safety and efficacy of RBL administered Graphical abstract:

Indexed as

CDIClostridioides difficilecolonoscopydysbiosislive biotherapeutic productmicrobiome-based therapeuticmicrobiome restorationmicrobiota-based therapeuticrCDI

Identifiers

PMID38529070
PMCPMC10962041
OpenAlexW4393169707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.