Evidence map›Paper›PMID 38529037›Full record

ArticleFrontiers in neurology2024

Treatment strategies and treatment-related adverse events in MG according to the age of onset.

João Moura, Joana Fernandes, Maria João Lima, Ana Paula Sousa, Raquel Samões, Ana Martins Silva, Ernestina Santos

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

João Moura *Department of Neurology, Centro Hospitalar Universitário de Santo António, Porto, Portugal.
Joana FernandesDepartment of Neurology, Centro Hospitalar Universitário de Santo António, Porto, Portugal.
Maria João LimaDepartment of Neurology, Unidade Local de Saúde de Matosinhos, Porto, Portugal.
Ana Paula SousaDepartment of Neurophysiology, Hospital de Santo António, Centro Hospitalar Universitário Do Porto, Porto, Portugal.
Raquel SamõesDepartment of Neurology, Centro Hospitalar Universitário de Santo António, Porto, Portugal.
Ana Martins SilvaDepartment of Neurology, Centro Hospitalar Universitário de Santo António, Porto, Portugal.
Ernestina SantosDepartment of Neurology, Centro Hospitalar Universitário de Santo António, Porto, Portugal.
Hospital de Santo António · PTUniversidade do Porto · PTAdministração Regional de Saúde de Lisboa e Vale do Tejo · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Early-onset (EOMG) and late-onset (LOMG) are distinct groups of MG patients. It is unclear if treatment strategies and treatment-related adverse events may differ according to the age of MG onset. Methods: This single-center retrospective study includes all MG patients followed at a tertiary center since 2007. We reviewed the electronic clinical records. Results: In total, 212 patients were identified, 142 (67.0%) females, with a median disease duration of 10 years. The median age of symptom onset was 42.0 (26.0-64.5) years, with 130 (61.3%) EOMG cases and 82 (38.7%) LOMG. EOMG were more frequently female, had longer disease duration and often more generalized MG ( Conclusion: Our study shows that treatment modalities are similar between EOMG and LOMG, while steroid-related adverse events appear to be distinct.

Indexed as

comorbiditiesimmunosuppressionlate-onsetmyasthenia gravissteroid-sparing

Identifiers

PMID38529037
PMCPMC10961456
OpenAlexW4392656457

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.