Evidence map›Paper›PMID 38529003›Full record

ArticleJAC-antimicrobial resistance2024

Carbapenem-resistant

Gert Marais, Clinton Moodley, Shantelle Claassen-Weitz, Fadheela Patel, Elizabeth Prentice, Hafsah Tootla, Nyasha Nyakutira, Katie Lennard, Kessendri Reddy, Colleen Bamford and 4 more

Abstract readComment
In one paragraph

Article in JAC-antimicrobial resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Clinical and microbiological epidemiology ofJAC-antimicrobial resistance · 2026
    Article
  6. Review
  7. Genomic Characterization ofOpen forum infectious diseases · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Frontiers in microbiology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Gert MaraisDivision of Medical Microbiology, University of Cape Town, Cape Town, Western Cape, South Africa.ORCID https://orcid.org/0000-0003-1477-6101
Clinton MoodleyDivision of Medical Microbiology, University of Cape Town, Cape Town, Western Cape, South Africa.ORCID https://orcid.org/0000-0001-7547-9026
Shantelle Claassen-WeitzDivision of Medical Microbiology, University of Cape Town, Cape Town, Western Cape, South Africa.
Fadheela PatelDivision of Medical Microbiology, University of Cape Town, Cape Town, Western Cape, South Africa.
Elizabeth PrenticeDivision of Medical Microbiology, University of Cape Town, Cape Town, Western Cape, South Africa.
Hafsah TootlaDivision of Medical Microbiology, University of Cape Town, Cape Town, Western Cape, South Africa.
Nyasha NyakutiraDivision of Medical Microbiology, University of Cape Town, Cape Town, Western Cape, South Africa.
Katie LennardDivision of Computational Biology, University of Cape Town, Cape Town, Western Cape, South Africa.
Kessendri ReddyDivision of Medical Microbiology, Stellenbosch University, Cape Town, Western Cape, South Africa.
Colleen BamfordDivision of Medical Microbiology, University of Cape Town, Cape Town, Western Cape, South Africa.
Abraham NiehausDivision of Medical Microbiology, Ampath, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-2793-1855
Andrew WhitelawDivision of Medical Microbiology, Stellenbosch University, Cape Town, Western Cape, South Africa.
Adrian BrinkDivision of Medical Microbiology, University of Cape Town, Cape Town, Western Cape, South Africa.ORCID https://orcid.org/0000-0002-5350-9690
Cape Town Antimicrobial Stewardship Study Alliance

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The molecular epidemiology of carbapenem-resistant Enterobacterales in Cape Town remains largely unknown. Objectives: This study aimed to describe the molecular epidemiology, resistome, virulome and mobilome of carbapenem-resistant Methods: Eighty-five CRKP isolates from hospitalized patients underwent WGS as part of a prospective, multicentre, cross-sectional study, conducted between 1 November 2020 and 30 November 2022, across public-sector and private-sector hospitals in Cape Town, South Africa. Results: MLST revealed three novel types, ST6785, ST6786 and ST6787, while the most common were ST219, ST307, ST17, ST13 and ST2497. Different predominant clones were noted in each hospital. The most common carbapenemase gene was Conclusions: CRKP epidemiology in Cape Town reflects institutionally dominant, rather than regional, clones. The most prevalent carbapenemase gene was

Identifiers

PMID38529003
PMCPMC10963078

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.