Evidence map›Paper›PMID 38528861›Full record

ArticleFrontiers in public health2024

Pre-pregnancy body mass index, gestational diabetes mellitus, and gestational weight gain: individual and combined effects on fetal growth.

Yanyu Lyu, Mingming Cui, Lingling Zhang, Guang Zheng, Hanxiao Zuo, Qingyong Xiu, Prakesh S Shah

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Double Burden of Malnutrition Prevalence in Pregnant Women: Systematic Review and Meta-Analysis.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Yanyu LyuExperiment Center, Capital Institute of Pediatrics, Beijing, China.
Mingming CuiBeijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.
Lingling ZhangRobert and Donna Manning College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA, United States.
Guang ZhengSchool of Information Science and Engineering, Lanzhou University, Lanzhou, China.
Hanxiao ZuoSchool of Public Health, University of Alberta, Edmonton, AB, Canada.
Qingyong XiuDepartment of Pediatrics, Beijing Daxing Maternal and Child Care Hospital, Beijing, China.
Prakesh S ShahDepartment of Pediatrics, Mount Sinai Hospital, Toronto, ON, Canada.
Capital Institute of Pediatrics · CNBeijing Obstetrics and Gynecology Hospital · CNLanzhou University · CNMount Sinai Hospital · CAUniversity of Alberta · CAUniversity of Massachusetts Boston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pre-pregnancy body mass index (BMI), gestational diabetes mellitus (GDM), and gestational weight gain (GWG) are interlinked and may play a complex role in fetal growth. We aimed to examine the relationship between pre-pregnancy BMI, GDM, GWG, and fetal growth outcomes and explore the contribution of GDM and GWG to the relationship between Pre-pregnancy obesity/overweight and large-for-gestational-age (LGA) in a prospective cohort. Methods: We prospectively recruited women in the first trimester and having one-step GDM screened with a 75-g oral glucose tolerance test between 24 and 28 weeks of gestation ( Results: Pre-pregnancy obesity, GDM, and excessive GWG were all independently associated with increased odds of LGA. Inadequate GWG was associated with higher odds of preterm birth. Compared with women unexposed to pre-pregnancy overweight/obesity, GDM, or excessive GWG, women exposed any two conditions had higher odds for LGA (AOR 3.18, 95% CI 1.25-8.11) and women with coexistence of all had the highest odds for LGA (AOR 8.09, 95% CI 2.18-29.97). The mediation analysis showed that GDM explained 18.60% ( Conclusion: Pre-pregnancy obesity/overweight, GDM, and excessive GWG are associated with higher odds of fetal growth disturbances as individual factors and when they co-exist. The effect of pre-pregnancy overweight/obesity on LGA is partially achieved through GDM and excessive GWG.

Indexed as

Diabetes, GestationalGestational Weight GainPremature BirthBody Mass IndexFemaleFetal DevelopmentHumansInfant, NewbornObesityOverweightPregnancyPregnancy OutcomeProspective StudiesWeight Gainbirth cohortgestational diabetes mellitusgestational weight gainlarge-for-gestational-agemediation analysispre-pregnancy body mass indexpreterm birth

Identifiers

PMID38528861
PMCPMC10961333
OpenAlexW4392656507

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.