Evidence map›Paper›PMID 38528847›Full record

ArticlePlastic and reconstructive surgery. Global open2024

Hyperbaric Oxygen Therapy for Diabetic Foot Ulcers Based on Wagner Grading: A Systematic Review and Meta-analysis.

Mendy Hatibie Oley, Maximillian Christian Oley, Billy Johnson Kepel, Muhammad Faruk, Angelica Maurene Joicetine Wagiu, Irawan Sukarno, Marcella Tirsa Tulong, Vania Sukarno

Open access · goldAbstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Observational
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  4. Review
  5. Review
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  7. Review
  8. Article
  9. [Research on the pathogenesis and treatment of diabetic foot ulcer wounds].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2025
    Review
  10. Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mendy Hatibie OleyFrom the Plastic Reconstructive and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Maximillian Christian OleyHyperbaric Centre Siloam Hospital, Manado, Indonesia.
Billy Johnson KepelDepartment of Chemistry, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Muhammad FarukDepartment of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Angelica Maurene Joicetine WagiuDepartment of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Irawan SukarnoDepartment of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Marcella Tirsa TulongHyperbaric Centre Siloam Hospital, Manado, Indonesia.
Vania SukarnoBangli General Hospital, Bangli, Indonesia.
Sam Ratulangi University · IDHasanuddin University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetic foot ulcers (DFUs) are common complications of uncontrolled diabetes mellitus that can result in infection and amputation of the lower extremities. This study compared the benefits and risks of hyperbaric oxygen therapy with those of other DFU treatments, based on the Wagner grading system. Methods: Systematic searches for randomly controlled trials using hyperbaric oxygen therapy for DFUs were performed using PubMed, the Cochrane Library, and Embase. Data regarding demographics, wound healing, minor and major amputations, operative debridement, nonhealing wounds, and adverse effects were analyzed based on Wagner grades, using RevMan 5.4.1 and Microsoft Excel. Results: Hyperbaric oxygen therapy was significantly superior to other treatments for wound healing rates 8 or more weeks after the final treatment (RR = 2.39; 1.87-3.05; Conclusions: Moderate-quality evidence revealed that adjunctive hyperbaric oxygen therapy improved DFU wound healing for Wagner grades II, III, and IV; prevented minor and major amputations for grades III and IV, respectively; and prevented operative debridement in grade II wounds.

Identifiers

PMID38528847
PMCPMC10962882
OpenAlexW4393166195

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.