Evidence map›Paper›PMID 38528306›Full record

ArticleInternational journal of computer assisted radiology and surgery2024

PitSurgRT: real-time localization of critical anatomical structures in endoscopic pituitary surgery.

Zhehua Mao, Adrito Das, Mobarakol Islam, Danyal Z Khan, Simon C Williams, John G Hanrahan, Anouk Borg, Neil L Dorward, Matthew J Clarkson, Danail Stoyanov and 2 more

Open access · hybridAbstract read
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Zhehua MaoDepartment of Computer Science, University College London, London, UK. z.mao@ucl.ac.uk.ORCID http://orcid.org/0000-0001-9225-6318
Adrito DasWellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.
Mobarakol IslamWellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.
Danyal Z KhanWellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.
Simon C WilliamsWellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.
John G HanrahanWellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.
Anouk BorgDepartment of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.
Neil L DorwardDepartment of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.
Matthew J ClarksonWellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.
Danail StoyanovDepartment of Computer Science, University College London, London, UK.
Hani J MarcusWellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.
Sophia BanoDepartment of Computer Science, University College London, London, UK.
Wellcome / EPSRC Centre for Interventional and Surgical Sciences · GBNational Hospital for Neurology and Neurosurgery · GB

Funding

Engineering and Physical Sciences Research Council EP/P012841/1Engineering and Physical Sciences Research Council EP/R004080/1Engineering and Physical Sciences Research Council EP/W00805X/1Engineering and Physical Sciences Research Council EP/Y01958X/1
6 · The paper itself

Abstract

purposeEndoscopic pituitary surgery entails navigating through the nasal cavity and sphenoid sinus to access the sella using an endoscope. This procedure is intricate due to the proximity of crucial anatomical structures (e.g. carotid arteries and optic nerves) to pituitary tumours, and any unintended damage can lead to severe complications including blindness and death. Intraoperative guidance during this surgery could support improved localization of the critical structures leading to reducing the risk of complications.

methodsA deep learning network PitSurgRT is proposed for real-time localization of critical structures in endoscopic pituitary surgery. The network uses high-resolution net (HRNet) as a backbone with a multi-head for jointly localizing critical anatomical structures while segmenting larger structures simultaneously. Moreover, the trained model is optimized and accelerated by using TensorRT. Finally, the model predictions are shown to neurosurgeons, to test their guidance capabilities.

resultsCompared with the state-of-the-art method, our model significantly reduces the mean error in landmark detection of the critical structures from 138.76 to 54.40 pixels in a 1280

conclusionThe results from the quantitative evaluation, real-time acceleration, and neurosurgeon study demonstrate the proposed method is highly promising in providing real-time intraoperative guidance of the critical anatomical structures in endoscopic pituitary surgery.

Indexed as

EndoscopyPituitary NeoplasmsDeep LearningHumansPituitary GlandSphenoid SinusSurgery, Computer-AssistedLandmark detectionPituitary tumourSegmentationSurgical scene understanding

Identifiers

PMID38528306
PMCPMC11178578
OpenAlexW4393164778

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.