Evidence map›Paper›PMID 38528214›Full record

Observational studyObesity surgery2024

Changes in Serum Urate Levels after Bariatric Surgery in Patients with Obesity: An Observational Study.

Daniel W Mills, Dylan M Woolley, Basil J Ammori, Hector Chinoy, Akheel A Syed

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Obesity surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Daniel W MillsGeneral (Internal) Medicine, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford, UK.
Dylan M WoolleyGeneral (Internal) Medicine, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford, UK.
Basil J AmmoriMetabolic and Bariatric Surgery, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford, UK.
Hector ChinoyFaculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Akheel A SyedFaculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK. akheel.syed@manchester.ac.uk.ORCID 0000-0001-8696-7121
Salford Royal Hospital · GBManchester Academic Health Science Centre · GBSalford Royal NHS Foundation Trust · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is a risk factor for hyperuricemia and gout, while weight reduction can reduce urate levels. The aim of this study was to examine the effect of bariatric surgery on longitudinal serum urate levels.

methodsWe performed a retrospective observational study of 283 patients who had undergone bariatric surgery [237 (83.7%) gastric bypass, 34 (12.0%) sleeve gastrectomy and 12 (4.2%) gastric banding] and were followed up for 2 years. The results shown represent mean (standard deviation).

resultsBariatric surgery was associated with significant reduction in serum urate from baseline level of 0.343 (0.086) mmol/L to 0.296 (0.076) mmol/L (p < 0.001) at 12 months and 0.286 (0.073) mmol/L (p < 0.001) at 24 months, including in men and women, and in patients with or without diabetes. Patients with elevated urate levels at baseline, who comprised 27.2% of the total cohort, achieved reduction in levels by 4 months.

conclusionBariatric surgery leads to significant reduction in serum urate levels at 12 and 24 months. This could reduce incidence of gout and need for prophylactic medication(s).

Indexed as

Bariatric SurgeryGastric BypassGoutObesity, MorbidFemaleGastrectomyHumansMaleObesityRetrospective StudiesTreatment OutcomeUric AcidUric AcidGastric bypassGoutHyperuricaemiaUric acidWeight loss

Identifiers

PMID38528214
PMCPMC11031430
OpenAlexW4393143094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.