Evidence map›Paper›PMID 38528168›Full record

ArticleNature medicine2024

Risk factors associated with heatwave mortality in Chinese adults over 65 years.

Di Xi, Linxin Liu, Min Zhang, Cunrui Huang, Katrin G Burkart, Kristie Ebi, Yi Zeng, John S Ji

Abstract read
PubMed Publisher
In one paragraph

Article in Nature medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  15. Heatwave Exposure Accelerates Biological Aging via Metabolic Dysregulation.Cyborg and bionic systems (Washington, D.C.) · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Di XiVanke School of Public Health, Tsinghua University, Beijing, China.
Linxin LiuVanke School of Public Health, Tsinghua University, Beijing, China.
Min ZhangVanke School of Public Health, Tsinghua University, Beijing, China.
Cunrui HuangVanke School of Public Health, Tsinghua University, Beijing, China.ORCID 0000-0002-9139-8354
Katrin G BurkartInstitute for Health Metric and Evaluation, University of Washington, Seattle, WA, USA.
Kristie EbiCenter for Health and the Global Environment, University of Washington, Seattle, WA, USA.ORCID 0000-0003-4746-8236
Yi ZengCenter for Healthy Aging and Development Studies, National School of Development, Peking University, Beijing, China.
John S JiVanke School of Public Health, Tsinghua University, Beijing, China. johnji@tsinghua.edu.cn.ORCID 0000-0002-5002-118X

Funding

THE RANGE OF MALE-FEMALE MORTALITY DIFFERENCESP01AG031719 · NIA · DUKE UNIVERSITY · PI CHRISTENSEN, KAARE · 2009 to 2020
$10.2M
National Natural Science Foundation of China (National Science Foundation of China) 82250610230Natural Science Foundation of Beijing Municipality (Beijing Natural Science Foundation) IS23105NIA NIH HHS P01 AG031719Tsinghua University (THU) 20233080015U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) P01AG031719
6 · The paper itself

Abstract

Aging populations are susceptible to heat-related mortality because of physiological factors and comorbidities. However, the understanding of individual vulnerabilities in the aging population is incomplete. In the Chinese Longitudinal Healthy Longevity Survey, we assessed daily heatwave exposure individually for 13,527 participants (median age = 89 years) and 3,249 summer mortalities during follow-up from 2008 to 2018. The mortality risk during heatwave days according to relative temperature is approximately doubled (hazard ratio (HR) range = 1.78-1.98). We found that heatwave mortality risks were increased for individuals with functional declines in mobility (HR range = 2.32-3.20), dependency in activities of daily living (HR range = 2.22-3.27), cognitive impairment (HR = 2.22) and social isolation reflected by having nobody to ask for help during difficulties (HR range = 2.14-10.21). Contrary to current understanding, older age was not predictive of heatwave mortality risk after accounting for individual functional declines; no statistical differences were detected according to sex. Beyond age as a risk factor, our findings emphasize that functional aging is an underlying factor in enhancing heatwave resilience. Assessment of functional decline and implementing care strategies are crucial for targeted prevention of mortality during heatwaves.

Indexed as

Activities of Daily LivingAgedAged, 80 and overAgingChinaEast Asian PeopleExtreme HeatFemaleHot TemperatureHumansLongitudinal StudiesMaleRisk Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.