Evidence map›Paper›PMID 38528118›Full record

ArticleActa pharmacologica Sinica2024

Disfunction of dorsal raphe nucleus-hippocampus serotonergic-HTR3 transmission results in anxiety phenotype of Neuroplastin 65-deficient mice.

Jie Cheng, Ling Chen, Ya-Ni Zheng, Juan Liu, Lei Zhang, Xiao-Ming Zhang, Liang Huang, Qiong-Lan Yuan

Open access · greenAbstract read
In one paragraph

Article in Acta pharmacologica Sinica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jie ChengDepartment of Neurology, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China.
Ling ChenDepartment of Neurology, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China.
Ya-Ni ZhengDepartment of Neurology, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China.
Juan LiuChinese Institute for Brain Research, Beijing, 102206, China.
Lei ZhangDepartment of Neurology, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China.
Xiao-Ming ZhangDepartment of Neurology, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China.
Liang HuangDepartment of Neurology, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China.
Qiong-Lan YuanDepartment of Neurology, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China. yqiongl@tongji.edu.cn.
Tongji Hospital · CNChinese Institute for Brain Research · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anxiety disorders are the most common psychiatric condition, but the etiology of anxiety disorders remains largely unclear. Our previous studies have shown that neuroplastin 65 deficiency (NP65

Indexed as

AnxietyDorsal Raphe NucleusHippocampusMice, KnockoutReceptors, Serotonin, 5-HT3SerotoninTryptophan HydroxylaseAnimalsLong-Term PotentiationMaleMiceMice, Inbred C57BLPhenotypeReceptors, Serotonin, 5-HT3SerotoninTph2 protein, mouseTryptophan Hydroxylaseanxiety disordersdorsal raphe nucleusLmx1bneuroplastin 65serotonergic transmissiontryptophan hydroxylase 2

Identifiers

PMID38528118
PMCPMC11192762
OpenAlexW4393155887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.