ArticleRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
Chronic sclerosing sialadenitis of the bilateral submandibular glands in childhood - a diagnostic dilemma.
Article in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 1 citations in OpenAlex.
- Histologically confirmed immunoglobulin G4-related hypophysitis in an adolescent girl: a case report with review of literature.Endocrine journal · 2025Review
- The Management of IgG4-Related Disease in Children: A Systematic Review.Children (Basel, Switzerland) · 2025Review
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7 authors at 3 institutions in 1 country.
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Abstract
Chronic sclerosing sialadenitis (CSS), currently included in the group of immunoglobulin G4 (IgG4)-related diseases, is an under-recognized inflammatory lesion that afflicts mostly the submandibular gland of 40-60 years adults. To our knowledge, only one case of CSS located in the submandibular gland has been reported in childhood to date. We present a case of CSS in a 5-year-old male child. He presented with bilateral submandibular swellings that clinically resembled discrete lumps, suspected to be tumors. The completely resected tumors composed predominantly of dense lymphoplasmacytic inflammatory infiltrate rich in IgG4-positive cells [77-90 IgG(+) cells per high-power field; IgG4(+)∕IgG(+) cells ratio of 42.77%]. We discuss the peculiarities of this case, and we also review the literature on CSS.
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