Evidence map›Paper›PMID 38527780›Full record

ReviewInfection & chemotherapy2024

Prevention of Cytomegalovirus Infection in Solid Organ Transplant Recipients: Guidelines by the Korean Society of Infectious Diseases and the Korean Society for Transplantation.

Kyungmin Huh, Sang-Oh Lee, Jungok Kim, Su Jin Lee, Pyoeng Gyun Choe, Ji-Man Kang, Jaeseok Yang, Heungsup Sung, Si-Ho Kim, Chisook Moon and 12 more

Open access · goldAbstract readReview
In one paragraph

Review in Infection & chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 11 institutions in 2 countries.

Kyungmin HuhDivision of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5140-3964
Sang-Oh LeeDepartment of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. soleemd@amc.seoul.kr.ORCID https://orcid.org/0000-0003-1381-8787
Jungok KimDivision of Infectious Diseases, Department of Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-0694-1579
Su Jin LeeDivision of Infectious Diseases, Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, Korea.ORCID https://orcid.org/0000-0003-1907-9102
Pyoeng Gyun ChoeDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-6794-7918
Ji-Man KangDepartment of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0678-4964
Jaeseok YangDepartment of Internal Medicine, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-5378-7797
Heungsup SungDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6062-4451
Si-Ho KimDivision of Infectious Diseases, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.ORCID https://orcid.org/0000-0001-7763-8940
Chisook MoonDivision of Infectious Diseases, Department of Internal Medicine, Inje University Busan Paik Hospital, College of Medicine, Busan, Korea.ORCID https://orcid.org/0000-0002-9063-9312
Hyeri SeokDivision of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Korea University Medicine, Ansan, Korea.ORCID https://orcid.org/0000-0002-2032-9538
Hye Jin ShiDivision of Infectious Diseases, Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea.ORCID https://orcid.org/0000-0002-7571-8485
Yu Mi WiDivision of Infectious Diseases, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.ORCID https://orcid.org/0000-0003-3625-3328
Su Jin JeongDivision of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4025-4542
Wan Beom ParkDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0022-9625
Youn Jeong KimDivision of Infectious Diseases, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.ORCID https://orcid.org/0000-0001-5870-1801
Jongman KimDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-1903-8354
Hyung Joon AhnDepartment of Surgery, College of Medicine, Kyung Hee University, Seoul, Korea.ORCID https://orcid.org/0000-0002-7427-0746
Nam Joong KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-6793-9467
Kyong Ran PeckDivision of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7464-9780
Myoung Soo KimDepartment of Surgery, The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8975-8381
Sang Il KimDepartment of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0002-2758-0012
Yonsei University · KRSamsung (South Korea) · KRSeoul National University · KRUlsan College · KRChungnam National University · KRSamsung Medical Center · KRAnsan University · KRGachon University Gil Medical Center · KRInje University Busan Paik Hospital · KRKyung Hee University · KRThe Catholic University of Korea Incheon St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus (CMV) is the most important opportunistic viral pathogen in solid organ transplant (SOT) recipients. The Korean guideline for the prevention of CMV infection in SOT recipients was developed jointly by the Korean Society for Infectious Diseases and the Korean Society of Transplantation. CMV serostatus of both donors and recipients should be screened before transplantation to best assess the risk of CMV infection after SOT. Seronegative recipients receiving organs from seropositive donors face the highest risk, followed by seropositive recipients. Either antiviral prophylaxis or preemptive therapy can be used to prevent CMV infection. While both strategies have been demonstrated to prevent CMV infection post-transplant, each has its own advantages and disadvantages. CMV serostatus, transplant organ, other risk factors, and practical issues should be considered for the selection of preventive measures. There is no universal viral load threshold to guide treatment in preemptive therapy. Each institution should define and validate its own threshold. Valganciclovir is the favored agent for both prophylaxis and preemptive therapy. The evaluation of CMV-specific cell-mediated immunity and the monitoring of viral load kinetics are gaining interest, but there was insufficient evidence to issue recommendations. Specific considerations on pediatric transplant recipients are included.

Indexed as

CytomegalovirusOrgan transplantationPrevention

Identifiers

PMID38527780
PMCPMC10990892
OpenAlexW4392869572

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.