Evidence map›Paper›PMID 38527226›Full record

ArticleACS chemical biology2024

Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria.

Drew V Carson, Reecan J Juarez, Truc Do, Zhongyue J Yang, A James Link

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS chemical biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Tangled Tail of Mechanically Interlocked Peptides.Journal of the American Chemical Society · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Drew V CarsonDepartment of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0002-4209-2199
Reecan J JuarezChemical and Physical Biology Program, Vanderbilt University, Nashville, Tennessee 37235, United States.
Truc DoDepartment of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey 08544, United States.
Zhongyue J YangDepartment of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.ORCID 0000-0003-0395-6617
A James LinkDepartment of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0001-5066-9691
Princeton University · USVanderbilt University · US

Funding

Lasso Peptide DiscoveryR01GM107036 · NIGMS · PRINCETON UNIVERSITY · PI LINK, AARON JAMES · 2014 to 2022
$2.9M
NIGMS NIH HHS R01 GM107036
6 · The paper itself

Abstract

The development of new antimicrobial agents effective against Gram-negative bacteria remains a major challenge in drug discovery. The lasso peptide cloacaenodin has potent antimicrobial activity against multiple strains in the

Indexed as

Antimicrobial PeptidesAnti-Bacterial AgentsBacteriaBacterial ProteinsEnterobacterMembrane ProteinsMembrane Transport ProteinsMolecular Dynamics SimulationPeptidesAnti-Bacterial AgentsAntimicrobial PeptidesBacterial ProteinsMembrane ProteinsMembrane Transport ProteinsPeptidestonB protein, Bacteria

Identifiers

PMID38527226
PMCPMC11031277
OpenAlexW4393162170

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.