Evidence map›Paper›PMID 38527194›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Improved RNA stability estimation through Bayesian modeling reveals most

Laura Jenniches, Charlotte Michaux, Linda Popella, Sarah Reichardt, Jörg Vogel, Alexander J Westermann, Lars Barquist

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. How Salmonella Works Under Osmotic and Desiccation Stresses.Comprehensive reviews in food science and food safety · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Mechanistic Studies of Antibacterial PNAs by RNA-Seq Analysis.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. APEX2 proximity labeling of RNA in bacteria.bioRxiv : the preprint server for biology · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Improved RNA stability estimation through Bayesian modeling reveals mostProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Laura JennichesHelmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, Würzburg 97080, Germany.ORCID 0000-0001-8455-3195
Charlotte MichauxInstitute of Molecular Infection Biology, University of Würzburg, Würzburg 97080, Germany.ORCID 0000-0003-1089-7846
Linda PopellaInstitute of Molecular Infection Biology, University of Würzburg, Würzburg 97080, Germany.ORCID 0000-0002-5309-5838
Sarah ReichardtHelmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, Würzburg 97080, Germany.ORCID 0009-0009-7414-7893
Jörg VogelHelmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, Würzburg 97080, Germany.ORCID 0000-0003-2220-1404
Alexander J WestermannHelmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, Würzburg 97080, Germany.ORCID 0000-0003-3236-0169
Lars BarquistHelmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, Würzburg 97080, Germany.ORCID 0000-0003-4732-2667
University of Würzburg · DEHelmholtz Centre for Infection Research · DEUniversity of Toronto · CA

Funding

Bayerisches Staatsministerium für Bildung und Kultus, Wissenschaft und Kunst (Bavarian State Ministry of Education, Science and the Arts) bayresq.net
6 · The paper itself

Abstract

RNA decay is a crucial mechanism for regulating gene expression in response to environmental stresses. In bacteria, RNA-binding proteins (RBPs) are known to be involved in posttranscriptional regulation, but their global impact on RNA half-lives has not been extensively studied. To shed light on the role of the major RBPs ProQ and CspC/E in maintaining RNA stability, we performed RNA sequencing of

Indexed as

Gene Expression ProfilingRifampinBayes TheoremHalf-LifeRNARNA-Binding ProteinsRNA StabilitySalmonellaTranscriptomeRifampinRNARNA-Binding ProteinsbacteriaBayesian statisticsRNA-binding proteinsRNA decayRNA-seq

Identifiers

PMID38527194
PMCPMC10998600
OpenAlexW4393164291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.