Evidence map›Paper›PMID 38527006›Full record

ArticleVeterinary medicine and science2024

In vitro anti-Trichomonas gallinae effects of Ziziphus vulgaris L. and Camellia sinensis (L.) Kuntze extracts.

Behnam Rahimi, Farnaz Malekifard, Bijan Esmaeilnejad

Open access · goldAbstract read
In one paragraph

Article in Veterinary medicine and science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Behnam RahimiDVM graduate, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
Farnaz MalekifardDepartment of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.ORCID 0000-0002-4809-3782
Bijan EsmaeilnejadDepartment of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.ORCID 0000-0003-1781-5890
Urmia University · IR

Funding

Research Council of Urmia University
6 · The paper itself

Abstract

backgroundTrichomonas gallinae is a parasite that causes canker and severe loss and death, especially in young pigeons. Metronidazole (MTZ) is the recommended drug for treating avian trichomoniasis. Due to drug resistance, non-chemical alternatives, such as medicinal plant extracts, are also considered possible therapies for this disease.

objectivesThis study compares the antitrichomonal effects of MTZ with extracts of Camellia sinensis and Ziziphus vulgaris on T. gallinae in vitro.

methodsSamples of T. gallinae were taken from infected pigeons. Multi-well plates with different concentrations (5, 10, 25, 50 and 100 µg/mL) of plant extracts were used for the in vitro study.

resultsThe minimum inhibitory concentration (MIC) of C. sinensis extract was 25 µg/mL over 24 h, compared to 50 µg/mL for MTZ. The MIC value of the Z. vulgaris extracts was 50 µg/mL.

conclusionsThe results suggest that the extracts of Z. vulgaris and C. sinensis, as potential natural agents, could have anti-avian trichomoniasis properties. This study also shows that MTZ, C. sinensis and Z. vulgaris are equally effective in preventing the growth of T. gallinae trophozoites in the culture.

Indexed as

Camellia sinensisTrichomonasTrichomonas InfectionsZiziphusAnimalsAntitrichomonal AgentsColumbidaeMetronidazoleAntitrichomonal AgentsMetronidazoleCamellia sinensis (L.) Kuntzein vitroTrichomonas gallinaeZiziphus vulgaris L. (jujube)

Identifiers

PMID38527006
PMCPMC10962798
OpenAlexW4393159174

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.