Evidence map›Paper›PMID 38526662›Full record

ReviewApplied biochemistry and biotechnology2024

Nano-delivery Systems and Therapeutic Applications of Phytodrug Mangiferin.

Madhuri Baghel, Ishita Baghel, Pramila Kumari, Meenakshi Bharkatiya, Garvita Joshi, Kalyani Sakure, Hemant Badwaik

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied biochemistry and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Madhuri BaghelApollo College of Pharmacy, Anjora, Durg, 491001, Chhattisgarh, India.
Ishita BaghelFoothill High School, 4375, Foothill Road, Pleasanton, CA, 94588, USA.
Pramila KumariM. J. College, Bhilai, 490023, Chhattisgarh, India.
Meenakshi BharkatiyaBhupal Nobles' Institute of Pharmaceutical Sciences, Bhupal Nobles' University, Udaipur, 313001, India.
Garvita JoshiMahakal Institute of Pharmaceutical Studies, Ujjain, India.
Kalyani SakureRungta College of Pharmaceutical Sciences and Research, Bhilai, 490023, CG, India.
Hemant BadwaikShri Shankaracharya Institute of Pharmaceutical Sciences and Research, Junwani, Bhilai, 490020, Chhattisgarh, India. hemantrbadwaik@gmail.com.ORCID http://orcid.org/0000-0003-4533-7363
Indian Institute of Technology Bhilai · INFoothill College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to cure a range of ailments, scientists have investigated a number of bioactive antioxidant compounds produced from natural sources. Mangiferin, a C-glycosyl xanthone-structured yellow polyphenol, is abundant in mangoes and other dietary sources. In-depth examinations found that it is effective in the treatment of a variety of disorders due to its antiviral, anti-inflammatory, antiproliferative, antigenotoxic, antiatherogenic, radioprotective, nephroprotective, antihyperlipidemic, and antidiabetic properties. However, it is recognised that mangiferin's poor bioavailability, volatility, and limited solubility restrict its therapeutic usefulness. Over time, effective solutions to these problems have arisen in the shape of effective delivery methods. The current articles present a summary of the several researches that have updated Mangiferin's biopharmaceutical characteristics. Additionally, strategies for enhancing the bioavailability, stability, and solubility of this phytodrug have been discussed. This review provides detailed information on the development of innovative Mangiferin delivery methods such as nanoparticles, liposomes, micelles, niosomes, microspheres, metal nanoparticles, and complexation, as well as its therapeutic applications in a variety of sectors. This article provides effective guidance for researchers who desire to work on the formulation and development of an effective delivery method for improved magniferin therapeutic effectiveness.

Indexed as

XanthonesAnimalsBiological AvailabilityDrug Delivery SystemsHumansLiposomesNanoparticle Drug Delivery SystemNanoparticlesLiposomesmangiferinNanoparticle Drug Delivery SystemXanthonesBioavailabilityMangiferinNano-delivery systemsPhytodrugXanthone

Identifiers

PMID38526662
OpenAlexW4393159652

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.