Evidence map›Paper›PMID 38526033›Full record

ArticleJournal of cellular and molecular medicine2024

Huayu Qutan Recipe promotes lipophagy and cholesterol efflux through the mTORC1/TFEB/ABCA1-SCARB1 signal axis.

Yue Li, Jiaxiang Pan, J J Jiajia Yu, Xize Wu, Guanlin Yang, Xue Pan, Guoyuan Sui, Mingyang Wang, Meijia Cheng, Shu Zhu and 9 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Pivotal Role of mTOR in Non-Skin Manifestations of Psoriasis.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 1 country.

Yue LiDepartment of Cardiology, the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China.ORCID 0000-0003-0994-8714
Jiaxiang PanDepartment of Cardiology, the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
J J Jiajia YuPostdoctoral Program of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Xize WuGraduate School of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Guanlin YangInnovation Engineering Technology Center of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Xue PanGraduate School of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Guoyuan SuiInnovation Engineering Technology Center of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Mingyang WangCollege of Animal Science and Veterinary Medicine of Shenyang Agricultural University, Shenyang, China.
Meijia ChengExperimental Center of Traditional Chinese Medicine, the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Shu ZhuDepartment of Paediatric Dentistry, School of Stomatology, China Medical University, Shenyang, China.
He TaiSchool of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, China.
Honghe XiaoSchool of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, China.
Lili XuDepartment of Cardiology, 924 Hospital of Joint Logistic Support Force of PLA, Guilin, China.
Jin WuInnovation Engineering Technology Center of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Yongju YangExperimental Center of Traditional Chinese Medicine, the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Jing TangDepartment of Cardiology, the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Lihong GongDepartment of Cardiology, the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Lianqun JiaInnovation Engineering Technology Center of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Dongyu MinExperimental Center of Traditional Chinese Medicine, the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Liaoning University of Traditional Chinese Medicine · CN81th Hospital of PLA · CNChina Medical University · CNNanjing University of Chinese Medicine · CNShenyang Agricultural University · CN

Funding

National Natural Science Foundation of China 81974548National Natural Science Foundation of China 82074145Open Fund of Key Laboratory of Theory and Application of Viscera- manifestation theory in Traditional Chinese Medicine, Ministry of Education, Liaoning University of TCM ZYZX1907Science and Technology Research of Education Department of Liaoning Province L201722Science and Technology Research Project of Education Department of Liaoning Province L202048The "Seedling Raising Project" of The Affiliated Hospital of Liaoning University of Chinese Medicine YM202109Youth Project of Basic Scientific Research Project of Education Department of Liaoning Province LJKQZ2021064
6 · The paper itself

Abstract

This study aims to investigate the mechanism of the anti-atherosclerosis effect of Huayu Qutan Recipe (HYQT) on the inhibition of foam cell formation. In vivo, the mice were randomly divided into three groups: CTRL group, MOD group and HYQT group. The HYQT group received HYQT oral administration twice a day (20.54 g/kg/d), and the plaque formation in ApoE

Indexed as

AtherosclerosisBoron CompoundsRibosomal Protein S6 Kinases, 70-kDaAnimalsApolipoproteins EAutophagyCholesterolFoam CellsMechanistic Target of Rapamycin Complex 1MiceMolecular Docking SimulationTaurineTOR Serine-Threonine Kinases4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneApolipoproteins EBoron CompoundsCholesterolMechanistic Target of Rapamycin Complex 1Ribosomal Protein S6 Kinases, 70-kDaTaurineTOR Serine-Threonine Kinasesautophagylipid metabolismmacrophageox‐LDL

Identifiers

PMID38526033
PMCPMC10962127
OpenAlexW4393160638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.