ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2024
Predictors of Mortality of Streptococcal Bacteremia and the Role of Infectious Diseases Consultation: A Retrospective Cohort Study.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 18 citations in OpenAlex.
- The Clinical Significance ofOpen forum infectious diseases · 2026Article
- Source Control inOpen forum infectious diseases · 2026Article
- Infective endocarditis treated surgically: correlation between imaging, and surgical findings.The international journal of cardiovascular imaging · 2026Article
- Short course of antimicrobial treatment for uncomplicated enterococcal bacteremia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Top unanswered questions in antimicrobial management of necrotizing soft tissue infections.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Review
- Infective Endocarditis and Antimicrobial Timing: A Case for Delay?Open forum infectious diseases · 2025Article
- Predictors of mortality of enterococcal bacteraemia and the role of source control interventions; a retrospective cohort study.Infection · 2025Article
- Evaluating Blood Culture Parameters to Identify Patients at Low Risk of Infective Endocarditis Among Those With Bacteremia by Gram-positive Cocci.Open forum infectious diseases · 2025Article
- Validation of the Proposed Definition for Complicated Coagulase-negative Staphylococcal Bacteremia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- Emerging Trends in Streptococcal Toxic Shock Syndrome, Japan.Emerging infectious diseases · 2025Article
- Factors Contributing to Delayed Initiation of Appropriate Antimicrobial Treatment in Patients With Streptococcal Bacteremia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- Review
- Oral antibiotic stepdown therapy for uncomplicated streptococcal bloodstream infections.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Evaluation of the HANDOC Score and the 2023 International Society of Cardiovascular Infectious Diseases and European Society of Cardiology Duke Clinical Criteria for the Diagnosis of Infective Endocarditis Among Patients With Streptococcal Bacteremia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
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Authors and funding
6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundStreptococcal bacteremia is associated with high mortality. Thia study aims to identify predictors of mortality among patients with streptococcal bacteremia.
methodsThis retrospective study was conducted at the Lausanne University Hospital, Switzerland, and included episodes of streptococcal bacteremia among adult patients from 2015 to 2023.
resultsDuring the study period, 861 episodes of streptococcal bacteremia were included. The majority of episodes were categorized in the Mitis group (348 episodes; 40%), followed by the Pyogenic group (215; 25%). Endocarditis was the most common source of bacteremia (164; 19%). The overall 14-day mortality rate was 8% (65 episodes). The results from the Cox multivariable regression model showed that a Charlson comorbidity index >4 (P .001; hazard ratio [HR], 2.87; confidence interval [CI]: 1.58-5.22), Streptococcus pyogenes (P = .011; HR, 2.54;CI: 1.24-5.21), sepsis (P < .001; HR, 7.48; CI: 3.86-14.47), lower respiratory tract infection (P = .002; HR, 2.62; CI: 1.42-4.81), and absence of source control interventions within 48 hours despite being warranted (P = .002; HR, 2.62; CI: 1.43-4.80) were associated with 14-day mortality. Conversely, interventions performed within 48 hours of bacteremia onset, such as infectious diseases consultation (P < .001; HR, 0.29; CI: .17-.48) and appropriate antimicrobial treatment (P < .001; HR, .28; CI: .14-.57), were associated with improved outcome.
conclusionsOur findings underscore the pivotal role of infectious diseases consultation in guiding antimicrobial treatment and recommending source control interventions for patients with streptococcal bacteremia.
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