Evidence map›Paper›PMID 38525138›Full record

ArticleToxicological research2024

A convenient spectrophotometric test for screening skin-sensitizing chemicals using reactivity with glutathione

Dong Ho Cha, Geon Ho Kim, Rahul U Nepal, Mahesh R Nepal, Tae Cheon Jeong

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicological research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Liproxstatin-1 Protects SH-SY5Y Cells by Inhibiting HInternational journal of molecular sciences · 2025
    Article
  3. Astaxanthin Inhibits HMarine drugs · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dong Ho ChaCollege of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan, 38541 Republic of Korea.
Geon Ho KimCollege of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan, 38541 Republic of Korea.
Rahul U NepalCollege of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan, 38541 Republic of Korea.
Mahesh R NepalCollege of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan, 38541 Republic of Korea.
Tae Cheon JeongCollege of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan, 38541 Republic of Korea.ORCID 0000-0003-2025-6698
Yeungnam University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To initiate skin sensitization, haptens react with endogenous proteins. During this process, skin sensitizers react with small endogenous molecules containing thiol or amino groups. In this study, a simple spectrophotometric method to identify skin sensitizers Supplementary Information: The online version contains supplementary material available at 10.1007/s43188-023-00218-9.

Indexed as

Alternative testGlutathioneIn chemicoSkin sensitizationSpectrophotometry

Identifiers

PMID38525138
PMCPMC10959841
OpenAlexW4389678190

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.