Evidence map›Paper›PMID 38524909›Full record

ArticleGlobal heart2024

India Hypertension Control Initiative: Blood Pressure Control Using Drug and Dose-Specific Standard Treatment Protocol at Scale in Punjab and Maharashtra, India, 2022.

Prabhdeep Kaur, Manikandanesan Sakthivel, Vettrichelvan Venkatasamy, Padmaja Jogewar, Sandeep S Gill, Abhishek Kunwar, Meenakshi Sharma, Anupam Khungar Pathni, Kiran Durgad, Swagata Kumar Sahoo and 13 more

Open access · goldAbstract read
In one paragraph

Article in Global heart, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 13 institutions in 5 countries.

Prabhdeep KaurICMR - National Institute of Epidemiology Author Institution is Unverified Chennai, IN.ORCID 0000-0002-2605-3739
Manikandanesan SakthivelDivision of Noncommunicable Diseases, ICMR-National Institute of Epidemiology, Chennai, IN.
Vettrichelvan VenkatasamyIHCI project, ICMR-National Institute of Epidemiology, Chennai, IN.ORCID 0000-0001-5142-9673
Padmaja JogewarState NCD Cell, Directorate of Health and Family Welfare, Government of Maharashtra, Mumbai, IN.
Sandeep S GillState NCD Cell, Directorate of Health and Family Welfare, Government of Punjab, Chandigarh, IN.
Abhishek KunwarDivision of Noncommunicable Diseases, WHO Country Office for India, New Delhi, IN.
Meenakshi SharmaDivision of Noncommunicable Diseases, Indian Council of Medical Research (ICMR), New Delhi, IN.
Anupam Khungar PathniIHCI project, Resolve to Save Lives, New Delhi, IN.ORCID 0000-0001-7582-0861
Kiran DurgadIHCI project, WHO Country Office for India, New Delhi, IN.
Swagata Kumar SahooIHCI project, Resolve to Save Lives, New Delhi, IN.
Amol WankhedeIHCI project, WHO Country Office for India, New Delhi, IN.
Navneet KumarIHCI project, State NCD Cell, Chandigarh (Punjab), WHO, IN.
Vishwajit BharadwajIHCI project, District NCD Cell, Bhandara (Maharashtra), WHO, IN.
Bidisha DasIHCI project, District NCD Cell, Bhatinda (Punjab), WHO, IN.
Tejpalsinh ChavanIHCI project, District NCD Cell, Pune (Maharashtra), WHO, IN.ORCID 0009-0002-5308-4802
Suhas KhedkarIHCI project, District NCD Cell, Satara (Maharashtra), WHO, IN.
Lalit SarodeIHCI project, District NCD Cell, Nashik (Maharashtra), WHO, IN.
Sampada D BangarDivision of Epidemiology and biostatistics, ICMR-National AIDS Research Institute, Pune, IN.
Ashish KrishnaIHCI project, Resolve to Save Lives, New Delhi, IN.
Roopa ShivashankarDivision of Noncommunicable Diseases, Indian Council of Medical Research (ICMR), New Delhi, IN.
Parasuraman GaneshkumarDivision of Noncommunicable Diseases, ICMR-National Institute of Epidemiology, Chennai, IN.ORCID 0000-0001-7466-7965
Pragati PragyaDivision of Noncommunicable Diseases, Indian Council of Medical Research (ICMR), New Delhi, IN.
Balram BhargavaDepartment of Health Research, MoHFW, Indian Council of Medical Research (ICMR), New Delhi, IN.
Indian Council of Medical Research · INNational Institute of Epidemiology · INSave the Children · BDNational Centre for Cell Science · INWorld Health Organization - India · INAção Educativa · BRDirectorate of Health · ISGovernment of Maharashtra · INIndian Numismatic, Historical and Cultural Research Foundation · INNational AIDS Research Institute · INNational Court Reporters Association · USPunjab State Council for Science & Technology · INWorld Health Organization Regional Office for South-East Asia · IN

Funding

World Health Organization 001
6 · The paper itself

Abstract

Background: Hypertension treatment coverage is low in India. A stepwise simple treatment protocol is one of the strategies to improve hypertension treatment in primary care. We estimated the effectiveness of various protocol steps to achieve blood pressure (BP) control in public sector health facilities in Punjab and Maharashtra, India, where the India Hypertension Control Initiative (IHCI) was implemented. Methods: We analyzed the records of people enrolled for hypertension treatment and follow-up under IHCI between January 2018 and December 2021 in public sector primary and secondary care facilities across 23 districts from two states. Each state followed a different treatment protocol. We calculated the proportion with controlled BP at each step of the protocol. We also estimated the mean decline in BP pre- and post-treatment. Results: Of 281,209 patients initiated on amlodipine 5 mg, 159,292 continued on protocol drugs and came for a follow-up visit during the first quarter of 2022. Of 33,450 individuals who came for the follow-up in Punjab and 125,842 in Maharashtra, 70% and 76% had controlled BP, respectively, at the first step with amlodipine 5 mg. In Punjab, at the second step with amlodipine 10 mg, the cumulative BP control increased to 75%. A similar 5% (76%-81%) increase was seen in the second step after adding telmisartan 40 mg in Maharashtra. Overall, the mean (SD) systolic blood pressure (SBP) decreased by 16 mmHg from 148 (15) mmHg at the baseline in Punjab. In Maharashtra, the decline in the mean (SD) SBP was about 15 mmHg from the 144 (18) mmHg baseline. Conclusion: Simple drug- and dose-specific protocols helped achieve a high control rate among patients retained in care under program conditions. We recommend treatment protocols starting with a single low-cost drug and escalating with the same or another antihypertensive drug depending on the cost and availability.

Indexed as

HypertensionAmlodipineAntihypertensive AgentsBlood PressureClinical ProtocolsHumansIndiaTreatment OutcomeAmlodipineAntihypertensive AgentsAntihypertensive AgentsBlood PressureClinical ProtocolsHypertensionIndiaNational Health ProgramsTreatment Outcome

Identifiers

PMID38524909
PMCPMC10959138
OpenAlexW4392957579

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.