Evidence map›Paper›PMID 38524600›Full record

ArticleHeliyon2024

Influence of inner ear impedance on middle ear sound transfer functions.

Sijia Zhai, Matthias Bornitz, Till Moritz Eßinger, Zhaoyu Chen, Marcus Neudert

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sijia ZhaiTechnische Universität Dresden, Faculty of Medicine Carl Gustav Carus, Department of Otorhinolaryngology Head and Neck Surgery, Ear Research Center Dresden (ERCD), Fetscherstraße 74, 01307, Dresden, Germany.
Matthias BornitzTechnische Universität Dresden, Faculty of Medicine Carl Gustav Carus, Department of Otorhinolaryngology Head and Neck Surgery, Ear Research Center Dresden (ERCD), Fetscherstraße 74, 01307, Dresden, Germany.
Till Moritz EßingerTechnische Universität Dresden, Faculty of Medicine Carl Gustav Carus, Department of Otorhinolaryngology Head and Neck Surgery, Ear Research Center Dresden (ERCD), Fetscherstraße 74, 01307, Dresden, Germany.
Zhaoyu ChenTechnische Universität Dresden, Faculty of Medicine Carl Gustav Carus, Department of Otorhinolaryngology Head and Neck Surgery, Ear Research Center Dresden (ERCD), Fetscherstraße 74, 01307, Dresden, Germany.
Marcus NeudertTechnische Universität Dresden, Faculty of Medicine Carl Gustav Carus, Department of Otorhinolaryngology Head and Neck Surgery, Ear Research Center Dresden (ERCD), Fetscherstraße 74, 01307, Dresden, Germany.
University Hospital Carl Gustav Carus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: For experimental studies on sound transfer in the middle ear, it may be advantageous to perform the measurements without the inner ear. In this case, it is important to know the influence of inner ear impedance on the middle ear transfer function (METF). Previous studies provide contradictory results in this regard. With the current study, we investigate the influence of inner ear impedance in more detail and find possible reasons for deviations in the previous studies. Methods: 11 fresh frozen temporal bones were prepared in our study. The factors related to inner ear impedance, including round window membrane stiffness, cochleostomy, cochlea fluid and cochlea destruction were involved in the experimental design. After measuring in the intact specimen as a reference (step 1), the round window membrane was punctured (step 2), then completely removed (step 3). The cochleostomy was performed (step 4) before the cochlear fluid was carefully suctioned through scala tympani (step 5) and scala vestibuli (step 6). Finally, cochlea was destroyed by drilling (step 7). Translational and rotational movement of the stapes footplate were measured and calculated at each step. The results of the steps were compared to quantify the effect of inner ear impedance changing related to the process of cochlear drainage. Results: As the inner ear impedance decreases from step 1 to 7, the amplitudes of the METF curves at each frequency gradually increase in general. From step 6 on, the measured METF are significantly different with respect to the intact group at high frequencies above 3 kHz. The differences are frequency dependent. However, the significant decrement of rotational motion appears at the frequencies above 4.5 kHz from the step 5. Conclusion: This study confirms the influence of inner ear impedance on METF only at higher frequencies (≥3 kHz). The rotational motions are more sensitive to the drainage of fluid at the higher frequency. Study results that found no influence of cochlea impedance may be due to incomplete drainage of the cochlea.

Indexed as

CochleostomyFootplate rotationInner ear impedanceMiddle ear transfer functionRound window stiffness

Identifiers

PMID38524600
PMCPMC10958710
OpenAlexW4392716730

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.