Evidence map›Paper›PMID 38524467›Full record

ArticleACS omega2024

Development of Poly(vinyl alcohol)-Chitosan Composite Nanofibers for Dual Drug Therapy of Wounds.

Badriyah S Alotaibi, Abida Kalsoom Khan, Zelal Kharaba, Haya Yasin, Rehana Yasmin, Munaza Ijaz, Madiha Khan, Ghulam Murtaza

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Badriyah S AlotaibiDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Abida Kalsoom KhanDepartment of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22044, Pakistan.
Zelal KharabaDepartment of Clinical Pharmacy, College of Pharmacy, AlAin University, Abu Dhabi Campus,Abu Dhabi 112612, United Arab Emirates.
Haya YasinDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman 346, United Arab Emirates.
Rehana YasminDepartment of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22044, Pakistan.
Munaza IjazDepartment of Microbiology, University of Central Punjab, Lahore 54000, Pakistan.
Madiha KhanDepartment of Microbiology, University of Central Punjab, Lahore 54000, Pakistan.
Ghulam MurtazaDepartment of Pharmacy, COMSATS University Islamabad, Lahore Campus,Lahore 54000, Pakistan.ORCID https://orcid.org/0000-0001-5649-5768
COMSATS University Islamabad · PKUniversity of Central Punjab · PKAbu Dhabi University · AEAjman University · AEPrincess Nourah bint Abdulrahman University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current trends in localized drug delivery are emphasizing the development of dual drug-loaded electrospun nanofibers (NFs) for an improved therapeutic effect on wounds, especially infected skin wounds. The objective of this study was to formulate a new healing therapy for an infected skin wound. To achieve this goal, this study involved the development and characterization of poly(vinyl alcohol) (PVA)/chitosan nanofibers loaded with ciprofloxacin and rutin hydrate. Polymers and drugs were used in different ratios. Nanofiber morphology was studied by scanning electron microscopy, thermal stability by thermogravimetric analysis, structural determination by the X-ray diffraction method, and integrity by Fourier transform infrared spectroscopy. Dissolution studies were performed to check the drug release behavior of the formulations. Antibacterial studies were performed against

Identifiers

PMID38524467
PMCPMC10955599
OpenAlexW4392544896

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.