Evidence map›Paper›PMID 38524220›Full record

ArticleF&S reports2024

Involvement of

Simon Guignard, Christina Guillaume, Laurie Tornero, Jessika Moreau, Manon Carles, François Isus, Éric Huyghe, Célia Ravel, Nathalie Vergnolle, Céline Deraison and 2 more

Open access · goldAbstract read
In one paragraph

Article in F&S reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Simon GuignardIRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Christina GuillaumeDepartment of Reproductive Medicine, Paule de Viguier Hospital, Toulouse Teaching Hospital Group Toulouse, France.
Laurie TorneroIRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Jessika MoreauDepartment of Reproductive Medicine, Paule de Viguier Hospital, Toulouse Teaching Hospital Group Toulouse, France.
Manon CarlesDepartment of Reproductive Medicine, Paule de Viguier Hospital, Toulouse Teaching Hospital Group Toulouse, France.
François IsusDepartment of Reproductive Medicine, Paule de Viguier Hospital, Toulouse Teaching Hospital Group Toulouse, France.
Éric HuygheDepartment of Reproductive Medicine, Paule de Viguier Hospital, Toulouse Teaching Hospital Group Toulouse, France.
Célia RavelUniv Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Rennes, France.
Nathalie VergnolleIRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Céline DeraisonIRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Chrystelle BonnartIRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Nicolas GatimelIRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Université Toulouse III - Paul Sabatier · FRHôpital Paule de Viguier · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the functional implications of a homozygous Design: Case report. Patients: Two twin brothers aged 30 years with hearing loss and unexplained infertility. Exposure or Intervention: Molecular genetic diagnosis of deafness. Evaluation of the acrosome reaction and calcium mobilization assays after induction by progesterone and ionomycin on spermatozoa of the Main Outcome Measures: Fertilization rate during conventional in vitro fertilization. Molecular genetic test. Percentage of acrosome-reacted spermatozoa with peanut agglutinin lectin staining. Recording of progesterone and ionomycin-induced intracellular calcium signals with a fluorescent probe. Results: Mr. S and his brother have normal, conventional sperm parameters. Both brothers have had repeated intrauterine insemination failures and one fertilization failure after conventional in vitro fertilization. Mr. S obtained 2 healthy babies after intracytoplasmic sperm injection. Genetic analysis found a homozygote deletion of the Conclusion: We demonstrate the absence of a calcium signal and acrosome reaction after progesterone in our patient with a

Indexed as

calcium channelcase reportCATSPERfertilizationhearing lossspermatozoa

Identifiers

PMID38524220
PMCPMC10958707
OpenAlexW4389987727

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.